"APC" Related Products

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Native Human Activated Protein C

Cat.No.: APC-001H
Product Overview: Native APC protein purified from human plasma.
Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
Source: Human Plasma
Species: Human
Form: 50% (vol/vol) Glycerol/H2O
Bio-activity: Activity is measured using a chromogenic substrate assay.
Molecular Mass: 56.2 kDa
Purity: >95% by SDS-PAGE
Storage: At -20 centigrade.
Gene Name: APC APC, WNT signaling pathway regulator [ Homo sapiens (human) ]
Official Symbol: APC
Synonyms: GS; DP2; DP3; BTPS2; DP2.5; PPP1R46; adenomatous polyposis coli protein; WNT signaling pathway regulator; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli (APC); deleted in polyposis 2.5; protein phosphatase 1, regulatory subunit 46; truncated adenomatosis polyposis coli
Gene ID: 324
mRNA Refseq: NM_000038
Protein Refseq: NP_000029
MIM: 611731
UniProt ID: P25054

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