Native Human Cystatin C (Cystatin 3)

• Cat.No.: CST3-8100H
• Product Overview: Human Cystatin C (Cystatin 3) was purified from Human Urine - chronic protein renal tubular proteinuria.

Specification

• Description: Cystatin C is a marker for allograph function in adult transplant patients. Cystatin C regulates extracellular cysteine protease activity, which results from microbial invasion or release of lysosomal proteinases from dying or diseased cells. It is freely filtered by the glomerular basement membrane (GBM) and serum concentration has been shown to correlate well with glomerular filtration rate (GFR).
• Source: Human Urine - chronic protein renal tubular proteinuria
• Species: Human
• Form: Frozen Liquid
• Molecular Mass: 13 kDa
• Purity: >95% pure by SDS PAGE
• Storage: -20°C

Gene Information

• Gene Name: CST3 cystatin C [ Homo sapiens ]
• Official Symbol: CST3
• Synonyms: CST3; cystatin C; cystatin C (amyloid angiopathy and cerebral hemorrhage); cystatin-C; cystatin 3; cystatin-3; gamma-trace; post-gamma-globulin; bA218C14.4 (cystatin C); neuroendocrine basic polypeptide; ARMD11; MGC117328
• Gene ID: 1471
• mRNA Refseq: NM_000099
• Protein Refseq: NP_000090
• MIM: 604312
• UniProt ID: P01034
• Chromosome Location: 20p11.2
• Pathway: Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; Salivary secretion, organism-specific biosystem; Salivary secretion, conserved biosystem
• Function: beta-amyloid binding; cysteine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; protease binding; protein binding