Native Pig Mucin 2 (MUC2) Protein
Cat.No. : | MUC2-28P |
Product Overview : | Native Mucin 2 (MUC2) Protein was purified from Sus scrofa (Pig). |
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- Gene Information
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Source : | Pig |
Species : | Pig |
Form : | Lyophilized from sterile PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 35.0kDa |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Reconstitute in PBS or others. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended. |
Official Symbol : | MUC2 |
Synonyms : | MLP; SMUC; Oligomeric Mucus/Gel-Forming; Mucin 2,Intestinal/Tracheal; MUC2 |
Official Symbol : | MUC2 |
Synonyms : | MLP; SMUC; Oligomeric Mucus/Gel-Forming; Mucin 2,Intestinal/Tracheal; MUC2 |
Products Types
◆ Recombinant Protein | ||
MUC2-672H | Recombinant Human MUC2 Protein (36-240 aa), His-SUMO-tagged | +Inquiry |
MUC2-1515H | Recombinant Human MUC2 Protein, GST tagged | +Inquiry |
Muc2-1803R | Recombinant Rat Muc2 Protein, His-tagged | +Inquiry |
MUC2-1146P | Recombinant Pig MUC2 Protein, His-tagged | +Inquiry |
MUC2-1466H | Recombinant Human MUC2 Protein (36-240 aa), His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe transcriptional regulation of MUC2 protein is regulated by a variety of signaling pathways and transcription factors, including methylation modification in the MUC2 promoter region, and regulation of transcription factors GATA4 and KLF4.
Yes, mutations in the MUC2 protein have been found to be associated with hereditary myxous enteropathy (HM), a rare intestinal disease caused primarily by mutations in the MUC2 protein that result in loss of function of the mucus layer.
MUC2 protein is involved in intestinal immune regulation by influencing intestinal microbes, regulating inflammatory response and antigen presentation, helping to maintain intestinal immune balance.
The shear variant of the MUC2 protein may have an important impact on its mucus layer formation and stability. Different shear variants may affect their adhesion and resistance to degradation.
Abnormal expression and functional defects of the MUC2 protein may lead to increased retention of microorganisms and harmful substances in the intestine, triggering intestinal inflammatory responses such as intestinal mucosal inflammation and destruction of the mucus layer.
By forming a mucus layer, MUC2 protein provides a protective barrier to the gut against harmful microorganisms, toxins and other external irritants from entering the intestinal mucosa.
Customer Reviews (3)
Write a reviewIt was observed that the expression level was high enough to meet the experimental requirements.
The use of this protein found high purity and no significant impurities.
Relatively active and able to efficiently perform the required biological activity experiments.
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