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Active Native Rat HNMT Protein

Cat.No. : HNMT-1355R
Product Overview : recombinant Rat HNMT protein was purified from rat Kidney.
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Description : Catalyzes the conversion of S-adenosyl-L-methionine and histamine to S-adenosyl-L-homocysteine and N(T) methylhistamine
Source : Rat Kidney
Species : Rat
Form : Freeze-dried powder
Bio-activity : 50-100 U/mg
Purity : 90% (biuret)
Unit Definition : The amount of enzyme which will convert one nanomole of histamine to methyl histamine per hour at pH 8.5 at 37 centigrade.
Storage : Store at -20 centigrade.
Publication :
Effects of leukoreduction on N-methylhistamine concentration in stored units of canine whole blood (2021)
Gene Name : Hnmt histamine N-methyltransferase [ Rattus norvegicus (Norway rat) ]
Official Symbol : Hnmt
Synonyms : HMT; Hnmt; histamine N-methyltransferase; EC 2.1.1.8
Gene ID : 81676
mRNA Refseq : NM_031044.3
Protein Refseq : NP_112306.1
UniProt ID : Q01984

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is there a link between HNMT and gastrointestinal disorders? 03/21/2021

Yes, HNMT dysfunction has been associated with gastrointestinal disorders, and understanding its role may open avenues for novel therapeutic strategies.

In what ways does HNMT play a role in the nervous system? 10/23/2017

HNMT is involved in the inactivation of histamine in the central nervous system, influencing neurotransmission and potentially impacting conditions like schizophrenia and anxiety disorders.

Can HNMT be used as a predictive marker for treatment response in certain conditions? 04/05/2017

Research is underway to investigate whether HNMT levels or activity could serve as predictive markers for treatment response in conditions where histamine regulation is implicated.

How does HNMT relate to drug metabolism and interactions? 01/14/2017

HNMT is involved in the metabolism of certain drugs, and variations in its activity can influence drug responses and potential interactions.

Can HNMT be a target for cancer therapy? 01/05/2017

Some studies suggest that HNMT may play a role in certain cancers, making it a potential target for therapeutic interventions. However, more research is needed in this area.

Customer Reviews (3)

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03/21/2018

    HNMT protein has been extensively studied and characterized, allowing researchers to confidently integrate it into their experimental workflows.

    01/17/2018

      Its unique properties and functions make it an essential component in investigating various biological processes and molecular mechanisms.

      02/26/2017

        Their prompt assistance and guidance contribute to enhancing the success and efficiency of my work with the HNMT protein.

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