Recombinant Active Human ACVR2B Protein, GST-tagged
Cat.No. : | ACVR2B-02H |
Product Overview : | Recombinant human ACVR2B (182-488) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. |
Source : | Insect cell |
Species : | Human |
Tag : | GST |
Molecular Mass : | Approx 61 kDa |
Protein length : | 182-488 |
Purity : | > 85% |
Stability : | One year at -70 centigrade from data of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μL |
Storage Buffer : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Shipping : | Dry ice |
Gene Name : | ACVR2B activin A receptor type 2B [ Homo sapiens (human) ] |
Official Symbol : | ACVR2B |
Synonyms : | ACVR2B; activin A receptor type 2B; HTX4; ACTRIIB; ActR-IIB; activin receptor type-2B; activin A receptor, type IIB; EC 2.7.11.30 |
Gene ID : | 93 |
mRNA Refseq : | NM_001106 |
Protein Refseq : | NP_001097 |
MIM : | 602730 |
UniProt ID : | Q13705 |
Products Types
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ACVR2B-011M | Active Recombinant Mouse ACVR2B Protein, Fc-tagged | +Inquiry |
ACVR2B-3386C | Active Recombinant Cynomolgus ACVR2B protein(Ser28-Thr143), His-tagged | +Inquiry |
ACVR2B-151R | Recombinant Rat ACVR2B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ACVR2B-2724HCL | Recombinant Human ACVR2B cell lysate | +Inquiry |
ACVR2B-2540MCL | Recombinant Mouse ACVR2B cell lysate | +Inquiry |
ACVR2B-734CCL | Recombinant Cynomolgus ACVR2B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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