Recombinant Bovine TARBP2 Protein (1-366 aa), His-Myc-tagged

• Cat.No.: TARBP2-2560B
• Product Overview: Recombinant Bovine TARBP2 Protein (1-366 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Microbiology. Protein Description: Full Length.

Specification

• Description: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
• Source: E. coli
• Species: Bovine
• Tag: His-Myc
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 45.8 kDa
• Protein length: 1-366 aa
• AA Sequence: MSEEEQGSGTTTGCGLPSIEQMLAA NPGKTPISLLQEYGTRIGKTPVYDL LKAEGQAHQPNFTFRVTVGDTSCTG QGPSKKAAKHKAAEVALKHLKGGSM LEPALEDSSSFSPLDSSLPEDVPVF TAAAAATPVPSAVPTRSSPMEVQPP VSPQQSECNPVGALQELVVQKGWRL PEYTVTQESGPAHRKEFTMTCRVER FIEIGSGTSKKLAKRNAAAKMLLRV HTVPLDARDGNEAEPEDDHFSIGVG SRLDGLRNRGPGCTWDSLRNSVGEK ILSLRSCSLGSLGALGPACCSVLSE LSEEQAFHVSYLDIEELSLSGLCQC LVELSTQPATVCHGSAATREAARGE AARRALQYLKIMAGSK
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: TARBP2 TARBP2 subunit of RISC loading complex [ Bos taurus (cattle) ]
• Official Symbol: TARBP2
• Synonyms: TARBP2
• Gene ID: 514674
• mRNA Refseq: NM_001075678
• Protein Refseq: NP_001069146
• UniProt ID: Q0IIG6