Recombinant Bovine TARBP2 Protein (1-366 aa), His-Myc-tagged TARBP2-2560B

Recombinant Bovine TARBP2 Protein (1-366 aa), His-Myc-tagged

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Recombinant Bovine TARBP2 Protein (1-366 aa), His-Myc-tagged

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Cat.No. : TARBP2-2560B
Product Overview : Recombinant Bovine TARBP2 Protein (1-366 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Microbiology. Protein Description: Full Length.
Description : Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
Source : E. coli
Species : Bovine
Tag : His-Myc
Form : Tris-based buffer,50% glycerol
Molecular Mass : 45.8 kDa
Protein length : 1-366 aa
AA Sequence : MSEEEQGSGTTTGCG LPSIEQMLAANPGKT PISLLQEYGTRIGKT PVYDLLKAEGQAHQP NFTFRVTVGDTSCTG QGPSKKAAKHKAAEV ALKHLKGGSMLEPAL EDSSSFSPLDSSLPE DVPVFTAAAAATPVP SAVPTRSSPMEVQPP VSPQQSECNPVGALQ ELVVQKGWRLPEYTV TQESGPAHRKEFTMT CRVERFIEIGSGTSK KLAKRNAAAKMLLRV HTVPLDARDGNEAEP EDDHFSIGVGSRLDG LRNRGPGCTWDSLRN SVGEKILSLRSCSLG SLGALGPACCSVLSE LSEEQAFHVSYLDIE ELSLSGLCQCLVELS TQPATVCHGSAATRE AARGEAARRALQYLK IMAGSK
Purity : > 85% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : TARBP2 TARBP2 subunit of RISC loading complex [ Bos taurus (cattle) ]
Official Symbol : TARBP2
Synonyms : TARBP2;
Gene ID : 514674
mRNA Refseq : NM_001075678
Protein Refseq : NP_001069146
UniProt ID : Q0IIG6

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