Recombinant Cattle CCL5 Protein, His-tagged

Cat.No. : CCL5-1206C
Product Overview : Recombinant Cattle CCL5 Protein (Ser24-Ser91) with His tag was expressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
Source : E. coli
Species : Cattle
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 9.4 kDa
Protein length : Ser24-Ser91
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in PBS or others.
Gene Name : CCL5 C-C motif chemokine ligand 5 [ Bos taurus (cattle) ]
Official Symbol : CCL5
Synonyms : CCL5; C-C motif chemokine ligand 5; RANTES; C-C motif chemokine 5; SIS-delta; T-cell-specific protein RANTES; chemokine (C-C motif) ligand 5; small-inducible cytokine A5
Gene ID : 327712
mRNA Refseq : NM_175827
Protein Refseq : NP_787021
UniProt ID : O97919

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the potential clinical applications of CCL5 inhibitors? 10/24/2021

CCL5 inhibitors may be used to control inflammation in diseases like rheumatoid arthritis or as an adjuvant in cancer therapy.

Can CCL5 be used to stimulate the immune system in cancer treatment? 10/24/2020

CCL5-based immunotherapies are being explored to enhance the immune response against cancer cells.

Can CCL5 be used as a diagnostic marker for diseases? 08/14/2019

It can serve as a biomarker for some diseases, but it is usually used in conjunction with other markers for more accurate diagnostics.

What are the clinical implications of elevated CCL5 levels? 02/20/2019

Elevated CCL5 levels are associated with inflammation and may be indicative of certain diseases such as rheumatoid arthritis or HIV infection.

Are there any CCL5-targeted therapies in development? 05/18/2018

Yes, there are ongoing efforts to develop therapies that modulate CCL5 activity, particularly in diseases involving inflammation.

Customer Reviews (3)

Write a review
Reviews
08/17/2021

    This specificity enables precise quantification and characterization of CCL5 and its interactions with other molecules or proteins of interest.

    06/23/2019

      Its exceptional performance, coupled with its ability to generate clear and precise protein bands, make it an indispensable tool in achieving accurate and reliable results.

      06/20/2016

        The CCL5 protein exhibits a high degree of specificity in various assays, ensuring accurate and reliable results.

        Ask a Question for All CCL5 Products

        Required fields are marked with *

        My Review for All CCL5 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends