Recombinant Cynomolgus CD86, His tagged
Cat.No. : | CD86-139C |
Product Overview : | Recombinant Cynomolgus CD86 (Q9BDM4) (Met1-His239), fused with a polyhistidine tag at the C-terminus, was produced in Human Cells. |
- Specification
- Gene Information
- Related Products
Source : | Human Cells |
Species : | Cynomolgus |
Tag : | His |
Predicted N Terminal : | Leu 20 |
Form : | Lyophilized from sterile PBS, PH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. |
Molecular Mass : | The recombinant cynomolgus CD86 comprises 231 amino acids and has a calculated molecular mass of 26.7 KDa. The apparent molecular mass of it is approximately 54-66 KDa respectively in SDS-PAGE. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD86?CD86 molecule [?Macaca fascicularis?(crab-eating macaque) ] |
Official Symbol : | CD86 |
Gene ID : | 102147235 |
mRNA Refseq : | XM_005547999 |
Protein Refseq : | XP_005548056 |
Chromosome Location : | 2 |
Products Types
◆ Recombinant Protein | ||
CD86-422H | Recombinant Human CD86 Protein (Met1-His239), His-Fc-tagged, Biotinylated | +Inquiry |
CD86-594H | Recombinant Human CD86 Protein | +Inquiry |
CD86-593C | Recombinant Cynomolgus monkey CD86 Protein, Fc-tagged | +Inquiry |
CD86-597M | Recombinant Mouse CD86 Protein, Fc-tagged | +Inquiry |
Cd86-40M | Recombinant Mouse CD86 Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
CD86-2598MCL | Recombinant Mouse CD86 cell lysate | +Inquiry |
CD86-1971RCL | Recombinant Rat CD86 cell lysate | +Inquiry |
CD86-2619HCL | Recombinant Human CD86 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, several clinical trials are investigating the efficacy of CD86 inhibitors in various diseases, including autoimmune disorders and certain cancers.
In transplantation, CD86 blockade is investigated as a potential strategy to modulate the immune response and prevent graft rejection by inhibiting excessive T cell activation.
CD86 signaling is involved in the differentiation of T helper cells. Modulating CD86 levels may influence the balance between Th1 and Th2 responses, which is relevant in various immune-mediated diseases.
There is emerging evidence suggesting that CD86 expression levels may have prognostic value in certain diseases, guiding clinicians in predicting disease outcomes.
CD86 signaling is involved in the development and function of regulatory T cells, which play a crucial role in maintaining immune tolerance and preventing autoimmune reactions.
Customer Reviews (3)
Write a reviewWith the CD86 protein's high-quality composition and reliability, researchers can confidently proceed with their studies, knowing that they have access to a protein that consistently delivers accurate results.
Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.
The CD86 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.
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