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Recombinant Cynomolgus Monkey CES1 Protein, His (Fc)-Avi-tagged

Cat.No. : CES1-151C
Product Overview : Recombinant Cynomolgus Monkey CES1 with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Cynomolgus Monkey
Tag : His&Fc&Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : CES1 carboxylesterase 1 [ Macaca fascicularis (crab-eating macaque) ]
Official Symbol : CES1
Synonyms : CES1;
Gene ID : 102129184
mRNA Refseq : NM_001283294
Protein Refseq : NP_001270223
UniProt ID : O46421

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
03/29/2022

    Reliable for lab work.

    09/16/2021

      Great value for quality.

      09/03/2020

        Good quality, great service.

        Q&As (7)

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        What is the primary function of the CES1 enzyme in the human body? 09/01/2022

        CES1 hydrolyzes ester and amide bonds in various compounds, including drugs, xenobiotics, and endogenous molecules.

        In which tissues or organs is CES1 most abundantly expressed? 07/10/2021

        CES1 is most abundantly expressed in the liver, playing a significant role in first-pass metabolism.

        How does CES1 contribute to drug metabolism? 09/14/2020

        It metabolizes numerous ester-containing drugs, affecting their pharmacokinetics and pharmacodynamics.

        What is the significance of CES1 in the metabolism of prodrugs? 05/04/2020

        CES1 is crucial for the activation of certain prodrugs, converting them into their active pharmacological forms.

        How can genetic variations in the CES1 gene affect drug response? 03/08/2020

        Genetic variations in CES1 can lead to inter-individual differences in drug metabolism, impacting efficacy and toxicity.

        Are there known inhibitors or activators of CES1, and how might they influence its activity? 04/06/2019

        Certain compounds can inhibit or activate CES1, altering the metabolism of its substrates.

        What role does CES1 play in lipid metabolism? 02/13/2018

        It participates in the hydrolysis of triglycerides and cholesterol esters, contributing to lipid homeostasis.

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