Recombinant Full Length Human ADARB1 Protein, C-Flag-tagged

• Cat.No.: ADARB1-450HFL
• Product Overview: Recombinant Full Length Human ADARB1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 80.6 kDa
• AA Sequence: MDIEDEENMSSSSTDVKENRNLDNV SPKDGSTPGPGEGSQLSNGGGGGPG RKRPLEEGSNGHSKYRLKKR RKTPGPVLPKNALMQLNEIKPGLQY TLLSQTGPVHAPLFVMSVEVNGQVF EGSGPTKKKAKLHAAEKALR SFVQFPNASEAHLAMGRTLSVNTDF TSDQADFPDTLFNGFETPDKAEPPF YVGSNGDDSFSSSGDLSLSA SPVPASLAQPPLPVLPPFPPPSGKN PVMILNELRPGLKYDFLSESGESHA KSFVMSVVVDGQFFEGSGRN KKLAKARAAQSALAAIFNLHLDQTP SRQPIPSEGLQLHLPQVLADAVSRL VLGKFGDLTDNFSSPHARRK VLAGVVMTTGTDVKDAKVISVSTGT KCINGEYMSDRGLALNDCHAEIISR RSLLRFLYTQLELYLNNKDD QKRSIFQKSERGGFRLKENVQFHLY ISTSPCGDARIFSPHEPILEGSRSY TQAGVQWCNHGSLQPRPPGL LSDPSTSTFQGAGTTEPADRHPNRK ARGQLRTKIESGEGTIPVRSNASIQ TWDGVLQGERLLTMSCSDKI ARWNVVGIQGSLLSIFVEPIYFSSI ILGSLYHGDHLSRAMYQRISNIEDL PPLYTLNKPLLSGISNAEAR QPGKAPNFSVNWTVGDSAIEVINAT TGKDELGRASRLCKHALYCRWMRVH GKVPSHLLRSKITKPNVYHE
  SKLAAKEYQAAKARLFTAFIKAGLG AWVEKPTEQDQFSLTPSGPTRTRRL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: ADARB1 adenosine deaminase RNA specific B1 [ Homo sapiens (human) ]
• Official Symbol: ADARB1
• Synonyms: RED1; ADAR2; DRABA2; DRADA2; NEDHYMS
• Gene ID: 104
• mRNA Refseq: NM_015833.4
• Protein Refseq: NP_056648.1
• MIM: 601218
• UniProt ID: P78563