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Recombinant Full Length Human AP5Z1 Protein, GST-tagged

Cat.No. : AP5Z1-1089HF
Product Overview : Human AP5Z1 full-length ORF ( AAH37399, 1 a.a. - 446 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 74.8 kDa
Protein Length : 446 amino acids
AA Sequence : MAKVVVLSPG TLQEDQATLL SKRLVDWLRY ASLQQGLPHS GGFFSTPRAR QPGPVTEVDG AVATDFFTVL SSGHRFTDDQ WLNVQAFSML RAWLLHSGPE GPGTLDTDDR SEQEGSTLSV ISATSSAGRL LPPRERLREV AFEYCQRLIE QSNRRALRKG DSDLQKACLV EAVLVLDVLC RQDPSFLYRS LSCLKALHGR VRGDPASVRV LLPLAHFFLS HGEAAAVDSE AVYQHLFTRI PVEQFHSPML AFEFIQFCRD NLHLFSGHLS TLRLSFPNLF KFLAWNSPPL TSEFVALLPA LVDAGTALEM LHALLDLPCL TAVLDLQLRS APAASERPLW DTSLRAPSCL EAFRDPQFQG LFQYLLRPKA SGATERLAPL HQLLQPMAGC ARVAQCAQAV PTLLQAFFSA VTQVADGSLI NQLALLLLGR SDSLYPAPGY AAGVHR
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : AP5Z1 adaptor related protein complex 5 zeta 1 subunit [ Homo sapiens (human) ]
Official Symbol : AP5Z1
Synonyms : AP5Z1; adaptor related protein complex 5 zeta 1 subunit; zeta; SPG48; KIAA0415; AP-5 complex subunit zeta-1; adapter-related protein complex 5 zeta subunit; adaptor-related protein complex 5 zeta subunit; zeta5
Gene ID : 9907
mRNA Refseq : NM_014855
Protein Refseq : NP_055670
MIM : 613653
UniProt ID : O43299

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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