Recombinant Human AP5Z1, His-tagged

• Cat.No.: AP5Z1-3545H
• Product Overview: AP-5 complex subunit zeta-1 (AP5Z1)

Specification

• Description: This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 807
• Purity: >90%
• Notes: Small volumes of AP5Z1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: AP5Z1 adaptor-related protein complex 5, zeta 1 subunit [ Homo sapiens ]
• Official Symbol: AP5Z1; AP-5 complex subunit zeta-1; zeta5; adapter-related protein complex 5 zeta subunit
• Synonyms: zeta; SPG48; KIAA0415
• Gene ID: 9907
• mRNA Refseq: NM_014855
• Protein Refseq: NP_055670
• UniProt ID: O43299
• Chromosome Location: 7p22.2
• Function: protein binding