Recombinant Full Length Human APBB3 Protein, GST-tagged

• Cat.No.: APBB3-1119HF
• Product Overview: Human APBB3 full-length ORF ( AAH13158, 1 a.a. - 486 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 79.20 kDa
• Protein Length: 486 amino acids
• AA Sequence: MLGKDYMLAI ILVNCDDDLW GDHSLEVEAG LPPGWRKIHD AAGTYYWHVP SGSTQWQRPT WELGDAEDPG TGTEGIWGLR PPKGRSFSSL ESSLDRSNSL SWYGGESYIQ SMEPGAKCFA VRSLGWVEVP EEDLAPGKSS IAVNNCIQQL AQTRSRSQPP DGAWGEGQNM LMILKKDAMS LVNPLDHSLI HCQPLVHIRV WGVGSSKGRD RDFAFVASDK DSCMLKCHVF RCDVPAKAIA SALHGLCAQI LSERVEVSGD ASCCSPDPIS PEDLPRQVEL LDAVSQAAQK YEALYMGTLP VTKAMGMDVL NEAIGTLTAR GDRNAWVPTM LSVSDSLMTA HPIQAEASTE EEPLWQCPVR LVTFIGVGRD PHTFGLIADL GRQSFQCAAF WCQPHAGGLS EAVQAACMVQ YQKCLVASAA RGKAWGAQAR ARLRLKRTSS MDSPGGPLPL PLLKGGVGGA GATPRKRGVF SLLDAFRLKP SLLHMP
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 [ Homo sapiens ]
• Official Symbol: APBB3
• Synonyms: APBB3; amyloid beta (A4) precursor protein-binding, family B, member 3; amyloid beta A4 precursor protein-binding family B member 3; FE65L2; FE65-like protein 2; protein Fe65-like 2; amyloid precursor interacting protein; SRA; MGC87674; MGC150555
• Gene ID: 10307
• mRNA Refseq: NM_006051
• Protein Refseq: NP_006042
• MIM: 602711
• UniProt ID: O95704