Recombinant Full Length Human B3GAT3 Protein, C-Flag-tagged

• Cat.No.: B3GAT3-1205HFL
• Product Overview: Recombinant Full Length Human B3GAT3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans. A pseudogene of this gene has been identified on chromosome 3.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 36.9 kDa
• AA Sequence: MKLKLKNVFLAYFLVSIAGLLYALV QLGQPCDCLPPLRAAAEQLRQKDLR ISQLQAELRRPPPAPAQPPE PEALPTIYVVTPTYARLVQKAELVR LSQTLSLVPRLHWLLVEDAEGPTPL VSGLLAASGLLFTHLVVLTP KAQRLREGEPGWVHPRGVEQRNKAL DWLRGRGGAVGGEKDPPPPGTQGVV YFADDDNTYSRELFEEMRWT RGVSVWPVGLVGGLRFEGPQVQDGR VVGFHTAWEPSRPFPVDMAGFAVAL PLLLDKPNAQFDSTAPRGHL
  ESSLLSHLVDPKDLEPRAANCTRVL VWHTRTEKPKMKQEEQLQRQGRGSD PAIEVTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Chondroitin sulfate biosynthesis, Heparan sulfate biosynthesis, Metabolic pathways

Gene Information

• Gene Name: B3GAT3 beta-1,3-glucuronyltransferase 3 [ Homo sapiens (human) ]
• Official Symbol: B3GAT3
• Synonyms: JDSCD; GLCATI; glcUAT-I
• Gene ID: 26229
• mRNA Refseq: NM_012200.4
• Protein Refseq: NP_036332.2
• MIM: 606374
• UniProt ID: O94766