| Species : |
Human |
| Source : |
In Vitro Cell Free System |
| Tag : |
GST |
| Protein Length : |
540 amino acids |
| Description : |
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
84.92 kDa |
| AA Sequence : |
MYENECECQL LLKEMLERLN KEADEALLHN LRLQLEAQFL QDDISAAKDR HKKNLLEVQT YISILQQIIH TTPPASIVTS GMREEKLLTE REVAALRSQL EEGREVLSHL QAQRVELQAQ TTTLEQAIKS AHECYDDEIQ LYNEQIETLR KEIEETERVL EKSSYDCRQL AVAQQTLKNE LDRYHRIIEI EGNRLTSAFI ETPIPLFTQS HGVSLSTGSG GKDLTRALQD ITAAKPRQKA LPKNVPRRKE IITKDKTNGA LEDAPLKGLE DTKLVQVVLK EESESKFESE SKEVSPLTQE GAPEDVPDGG QISKGFGKLY RKVKEKVRSP KEPETPTELY TKERHVLVTG DANYVDPRFY VSSITAKGGV AVSVAEDSVL YDGQVGPSPE SPKPPLENGQ VGLQEKEDGQ PIDQQPIDKE IEPDGAELEG PEEKREGEER DEESRRPCAM VTPGAEEPSI PEPPKPAADQ DGAEVLGTRS RSLPEKGPPK ALAYKTVEVV ESIEKISTES IQTYEETAVI VETMIGKTKS DKKKSGEKSS |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
