Recombinant Full Length Human BPIFA1 Protein, C-Flag-tagged

• Cat.No.: BPIFA1-989HFL
• Product Overview: Recombinant Full Length Human BPIFA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24.6 kDa
• AA Sequence: MFQTGGLIVFYGLLAQTMAQFGGLP VPLDQTLPLNVNPALPLSPTGLAGS LTNALSNGLLSGGLLGILEN LPLLDILKPGGGTSGGLLGGLLGKV TSVIPGLNNIIDIKVTDPQLLELGL VQSPDGHRLYVTIPLGIKLQ VNTPLVGASLLRLAVKLDITAEILA VRDKQERIHLVLGDCTHSPGSLQIS LLDGLGPLPIQGLLDSLTGI
  LNKVLPELVQGNVCPLVNEVLRGLD ITLVHDIVNMLIHGLQFVIKVTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: BPIFA1 BPI fold containing family A member 1 [ Homo sapiens (human) ]
• Official Symbol: BPIFA1
• Synonyms: LUNX; NASG; PLUNC; SPURT; SPLUNC1; bA49G10.5
• Gene ID: 51297
• mRNA Refseq: NM_016583.4
• Protein Refseq: NP_057667.1
• MIM: 607412
• UniProt ID: Q9NP55