Recombinant Full Length Human CALB1 Protein, C-Flag-tagged

• Cat.No.: CALB1-2030HFL
• Product Overview: Recombinant Full Length Human CALB1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 29.8 kDa
• AA Sequence: MAESHLQSSLITASQFFEIWLHFDA DGSGYLEGKELQNLIQELQQARKKA GLELSPEMKTFVDQYGQRDD GKIGIVELAHVLPTEENFLLLFRCQ QLKSCEEFMKTWRKYDTDHSGFIET EELKNFLKDLLEKANKTVDD TKLAEYTDLMLKLFDSNNDGKLELT EMARLLPVQENFLLKFQGIKMCGKE FNKAFELYDQDGNGYIDENE LDALLKDLCEKNKQDLDINNITTYK KNIMALSDGGKLYRTDLALILCAGD N TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CALB1 calbindin 1 [ Homo sapiens (human) ]
• Official Symbol: CALB1
• Synonyms: CALB; D-28K
• Gene ID: 793
• mRNA Refseq: NM_004929.4
• Protein Refseq: NP_004920.1
• MIM: 114050
• UniProt ID: P05937