Recombinant Full Length Human CBS Protein, GST-tagged
Cat.No. : | CBS-2776HF |
Product Overview : | Human CBS full-length ORF (AAH11381.1, 1 a.a. - 551 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 86.35 kDa |
Protein length : | 551 amino acids |
AA Sequence : | MPSETPQAEVGPTGCPHRSGPHSAK GSLEKGSPEDKEAKEPLWIRPDAPS RCTWQLGRPASESPHHHTAPAKSPK ILPDILKKIGDTPMVRINKIGKKFG LKCELLAKCEFFNAGGSVKDRISLR MIEDAERDGTLKPGDTIIEPTSGNT GIGLALAAAVRGYRCIIVMPEKMSS EKVDVLRALGAEIVRTPTNARFDSP ESHVGVAWRLKNEIPNSHILDQYRN ASNPLAHYDTTADEILQQCDGKLDM LVASVGTGGTITGIARKLKEKCPGC RIIGVDPEGSILAEPEELNQTEQTT YEVEGIGYDFIPTVLDRTVVDKWFK SNDEEAFTFARMLIAQEGLLCGGSA GSTVAVAVKAAQELQEGQRCVVILP DSVRNYMTKFLSDRWMLQKGFLKEE DLTEKKPWWWHLRVQELGLSAPLTV LPTITCGHTIEILREKGFDQAPVVD EAGVILGMVTLGNMLSSLLAGKVQP SDQVGKVIYKQFKQIRLTDTLGRLS HILEMDHFALVVHEQIQYHSTGKSS QRQMVFGVVTAIDLLNFVAAQERDQ K |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CBS cystathionine-beta-synthase [ Homo sapiens ] |
Official Symbol : | CBS |
Synonyms : | CBS; cystathionine-beta-synthase; cystathionine beta-synthase; HIP4; beta-thionase; serine sulfhydrase; methylcysteine synthase; |
Gene ID : | 875 |
mRNA Refseq : | NM_000071 |
Protein Refseq : | NP_000062 |
MIM : | 613381 |
UniProt ID : | P35520 |
Products Types
◆ Recombinant Protein | ||
CBS-0471H | Recombinant Human CBS Protein, GST-Tagged | +Inquiry |
CBS-514H | Recombinant Human CBS Protein, His (Fc)-Avi-tagged | +Inquiry |
CBS-111C | Recombinant Cynomolgus Monkey CBS Protein, His (Fc)-Avi-tagged | +Inquiry |
CBS-819R | Recombinant Rat CBS Protein, His (Fc)-Avi-tagged | +Inquiry |
Cbs-827M | Recombinant Mouse Cbs Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
CBS-7809HCL | Recombinant Human CBS 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1113 | Cystathionine β Synthase Activity Assay Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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