Active Recombinant Full Length Human CHD7 Protein, Flag tagged

• Cat.No.: CHD7-01HFL
• Product Overview: Recombinant CHD7 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_060250.2) with an N-terminal FLAG tag.

Specification

• Species: Human
• Source: E.coli
• Tag: Flag
• Protein Length: 1-2997 aa
• Description: CHD7 is one of the nine members of the chromodomain helicase DNA-binding family of ATP-dependent chromatin remodeling enzymes. CHD proteins are broadly classified into three subfamilies on the basis of their constituent domains: subfamily I (CHD1 and CHD2), subfamily II (CHD3, CHD4 and CHD5) and sub-family III (CHD6, CHD7, CHD8 and CHD9). CHD7 is the most extensively studied member of CHD subfamily III. Mutations in CHD7 give rise to CHARGE syndrome, a human condition characterized by malformation of various organs.
• Molecular Mass: 337.2 kDa
• Purity: ≥ 95%
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Gene Information

• Gene Name: CHD7 chromodomain helicase DNA binding protein 7 [ Homo sapiens (human) ]
• Official Symbol: CHD7
• Synonyms: CHD7; chromodomain helicase DNA binding protein 7; CRG; HH5; IS3; KAL5; ATP-dependent chromatin remodeler CHD7; chromodomain-helicase-DNA-binding protein 7; ATP-dependent helicase CHD7; CHARGE association; chromo domain-containing protein 7; NP_001303619.1; EC 3.6.4.12
• Gene ID: 55636
• mRNA Refseq: NM_001316690
• Protein Refseq: NP_001303619
• MIM: 608892
• UniProt ID: Q9P2D1