Recombinant Full Length Human COX15 Protein, GST-tagged

Cat.No. : COX15-1997HF
Product Overview : Human COX15 full-length ORF ( AAH02382.1, 1 a.a. - 410 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq, Jul 2008]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 70.73 kDa
Protein Length : 410 amino acids
AA Sequence : MQRLLFPPLRALKGRQYLPLLAPRA APRAQCDCIRRPLRPGQYSTISEVA LQSGRGTVSLPSKAAERVVGRWLLV CSGTVAGAVILGGVTRLTESGLSMV DWHLIKEMKPPTSQEEWEAEFQRYQ QFPEFKILNHDMTLTEFKFIWYMEY SHRMWGRLVGLVYILPAAYFWRKGW LSRGMKGRVLALCGLVCFQGLLGWY MVKSGLEEKSDSHDIPRVSQYRLAA HLGSALVLYCASLWTSLSLLLPPHK LPETHQLLQLRRFAHGTAGLVFLTA LSGAFVAGLDAGLVYNSFPKMGESW IPEDLFTFSPILRNVFENPTMVQFD HRILGITSVTAITVLYFLSRRIPLP RRTKMAAVTLLALAYTQVGLGISTL LMYVPTPLAATHQSGSLALLTGALW LMNELRRVPK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : COX15 COX15 homolog, cytochrome c oxidase assembly protein (yeast) [ Homo sapiens ]
Official Symbol : COX15
Synonyms : COX15; COX15 homolog, cytochrome c oxidase assembly protein (yeast); COX15 (yeast) homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15
Gene ID : 1355
mRNA Refseq : NM_004376
Protein Refseq : NP_004367
MIM : 603646
UniProt ID : Q7KZN9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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