Recombinant Human COX15 Protein, GST-tagged

• Cat.No.: COX15-1735H
• Product Overview: Human COX15 full-length ORF ( AAH02382.1, 1 a.a. - 410 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 70.73 kDa
• AA Sequence: MQRLLFPPLRALKGRQYLPLLAPRA APRAQCDCIRRPLRPGQYSTISEVA LQSGRGTVSLPSKAAERVVGRWLLV CSGTVAGAVILGGVTRLTESGLSMV DWHLIKEMKPPTSQEEWEAEFQRYQ QFPEFKILNHDMTLTEFKFIWYMEY SHRMWGRLVGLVYILPAAYFWRKGW LSRGMKGRVLALCGLVCFQGLLGWY MVKSGLEEKSDSHDIPRVSQYRLAA HLGSALVLYCASLWTSLSLLLPPHK LPETHQLLQLRRFAHGTAGLVFLTA LSGAFVAGLDAGLVYNSFPKMGESW IPEDLFTFSPILRNVFENPTMVQFD HRILGITSVTAITVLYFLSRRIPLP RRTKMAAVTLLALAYTQVGLGISTL LMYVPTPLAATHQSGSLALLTGALW LMNELRRVPK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COX15 COX15 homolog, cytochrome c oxidase assembly protein (yeast) [ Homo sapiens ]
• Official Symbol: COX15
• Synonyms: COX15; COX15 homolog, cytochrome c oxidase assembly protein (yeast); COX15 (yeast) homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly protein COX15 homolog; cytochrome c oxidase subunit 15
• Gene ID: 1355
• mRNA Refseq: NM_004376
• Protein Refseq: NP_004367
• MIM: 603646
• UniProt ID: Q7KZN9