Recombinant Full Length Human COX6A2 Protein, C-Flag-tagged

• Cat.No.: COX6A2-1741HFL
• Product Overview: Recombinant Full Length Human COX6A2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 9.4 kDa
• AA Sequence: MALPLRPLTRGLASAAKGGHGGAGA RTWRLLTFVLALPSVALCTFNSYLH SGHRPRPEFRPYQHLRIRTKPYPWG DGNHTLFHNSHVNPLPTGYEHPTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

Gene Information

• Gene Name: COX6A2 cytochrome c oxidase subunit 6A2 [ Homo sapiens (human) ]
• Official Symbol: COX6A2
• Synonyms: COX6AH; COXVIAH; MC4DN18; COXVIa-M
• Gene ID: 1339
• mRNA Refseq: NM_005205.4
• Protein Refseq: NP_005196.1
• MIM: 602009
• UniProt ID: Q02221