Recombinant Full Length Human CUL1 Protein, GST-tagged

• Cat.No.: CUL1-2394HF
• Product Overview: Human CUL1 full-length ORF ( NP_003583.2, 1 a.a. - 776 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: CUL1 (Cullin 1) is a Protein Coding gene. Diseases associated with CUL1 include Xeroderma Pigmentosum Group E and Parkinson Disease 15, Autosomal Recessive. Among its related pathways are IL-1 signaling pathway and Notch signaling pathway (KEGG). GO annotations related to this gene include ubiquitin protein ligase binding. An important paralog of this gene is CUL2.
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 116.1 kDa
• Protein Length: 776 amino acids
• AA Sequence: MSSTRSQNPHGLKQIGLDQIWDDLR AGIQQVYTRQSMAKSRYMELYTHVY NYCTSVHQSNQARGAGVPPSKSKKG QTPGGAQFVGLELYKRLKEFLKNYL TNLLKDGEDLMDESVLKFYTQQWED YRFSSKVLNGICAYLNRHWVRRECD EGRKGIYEIYSLALVTWRDCLFRPL NKQVTNAVLKLIEKERNGETINTRL ISGVVQSYVELGLNEDDAFAKGPTL TVYKESFESQFLADTERFYTRESTE FLQQNPVTEYMKKAEARLLEEQRRV QVYLHESTQDELARKCEQVLIEKHL EIFHTEFQNLLDADKNEDLGRMYNL VSRIQDGLGELKKLLETHIHNQGLA AIEKCGEAALNDPKMYVQTVLDVHK KYNALVMSAFNNDAGFVAALDKACG RFINNNAVTKMAQSSSKSPELLARY CDSLLKKSSKNPEEAELEDTLNQVM VVFKYIEDKDVFQKFYAKMLAKRLV HQNSASDDAEASMISKLKQACGFEY TSKLQRMFQDIGVSKDLNEQFKKHL TNSEPLDLDFSIQVLSSGSWPFQQS CTFALPSELERSYQRFTAFYASRHS GRKLTWLYQLSKGELVTNCFKNRYT LQASTFQMAILLQYNTEDAYTVQQL TDSTQIKMDILAQVLQILLKSKLLV LEDENANVDEVELKPDTLIKLYLGY KNKKLRVNINVPMKTEQKQEQETTH KNIEEDRKLLIQAAIVRIMKMRKVL KHQQLLGEVLTQLSSRFKPRVPVIK KCIDILIEKEYLERVDGEKDTYSYL A
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CUL1 cullin 1 [ Homo sapiens ]
• Official Symbol: CUL1
• Synonyms: CUL1; cullin 1; cullin-1; CUL-1; MGC149834; MGC149835
• Gene ID: 8454
• mRNA Refseq: NM_003592
• Protein Refseq: NP_003583
• MIM: 603134
• UniProt ID: Q13616