Recombinant Full Length Human FTCD Protein, C-Flag-tagged

• Cat.No.: FTCD-1103HFL
• Product Overview: Recombinant Full Length Human FTCD Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 58.7 kDa
• AA Sequence: MSQLVECVPNFSEGKNQEVIDAISG AITQTPGCVLLDVDAGPSTNRTVYT FVGPPECVVEGALNAARVAS RLIDMSRHQGEHPRMGALDVCPFIP VRGVSVDECVLCAQAFGQRLAEELD VPVYLYGEAARMDSRRTLPA IRAGEYEALPKKLQQADWAPDFGPS SFVPSWGATATGARKFLIAFNINLL GTKEQAHRIALNLREQGRGK DQPGRLKKVQGIGWYLDEKNLAQVS TNLLDFEVTALHTVYEETCREAQEL SLPVVGSQLVGLVPLKALLD AAAFYCEKENLFILEEEQRIRLVVS RLGLDSLCPFSPKERIIEYLVPERG PERGLGSKSLRAFVGEVGAR SAAPGGGSVAAAAAAMGAALGSMVG LMTYGRRQFQSLDTTMRRLIPPFRE ASAKLTTLVDADAEAFTAYL EAMRLPKNTPEEKDRRTAALQEGLR RAVSVPLTLAETVASLWPALQELAR CGNLACRSDLQVAAKALEMG
  VFGAYFNVLINLRDITDEAFKDQIH HRVSSLLQEAKTQAALVLDCLETRQ ETRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Histidine metabolism, Metabolic pathways, One carbon pool by folate

Gene Information

• Gene Name: FTCD formimidoyltransferase cyclodeaminase [ Homo sapiens (human) ]
• Official Symbol: FTCD
• Synonyms: LCHC1
• Gene ID: 10841
• mRNA Refseq: NM_006657.3
• Protein Refseq: NP_006648.1
• MIM: 606806
• UniProt ID: O95954