Recombinant Full Length Human GRB10 Protein, GST-tagged

• Cat.No.: GRB10-5319HF
• Product Overview: Human GRB10 full-length ORF ( NP_001001550.1, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 87.2 kDa
• Protein Length: 536 amino acids
• AA Sequence: MNASLESLYSACSMQSDTVPLLQNG QHARSQPRASGPPRSIQPQVSPRQR VQRSQPVHILAVRRLQEEDQQFRTS SLPAIPNPFPELCGPGSPPVLTPGS LPPSQAAAKQDVKVFSEDGTSKVVE ILADMTARDLCQLLVYKSHCVDDNS WTLVEHHPHLGLERCLEDHELVVQV ESTMASESKFLFRKNYAKYEFFKNP MNFFPEQMVTWCQQSNGSQTQLLQN FLNSSSCPEIQGFLHVKELGKKSWK KLYVCLRRSGLYCSTKGTSKEPRHL QLLADLEDSNIFSLIAGRKQYNAPT DHGLCIKPNKVRNETKELRLLCAED EQTRTCWMTAFRLLKYGMLLYQNYR IPQQRKALLSPFSTPVRSVSENSLV AMDFSGQTGRVIENPAEAQSAALEE GHAWRKRSTRMNILGSQSPLHPSTL STVIHRTQHWFHGRISREESHRIIK QQGLVDGLFLLRDSQSNPKAFVLTL CHHQKIKNFQILPCEDDGQTFFSLD DGNTKFSDLIQLVDFYQLNKGVLPC KLKHHCIRVAL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
• Official Symbol: GRB10
• Synonyms: GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207
• Gene ID: 2887
• mRNA Refseq: NM_001001549
• Protein Refseq: NP_001001549
• MIM: 601523
• UniProt ID: Q13322