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Recombinant Full Length Human GRB10 Protein, GST-tagged

Cat.No. : GRB10-5319HF
Product Overview : Human GRB10 full-length ORF ( NP_001001550.1, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 87.2 kDa
Protein length : 536 amino acids
AA Sequence : MNASLESLYSACSMQSDTVPLLQNG QHARSQPRASGPPRSIQPQVSPRQR VQRSQPVHILAVRRLQEEDQQFRTS SLPAIPNPFPELCGPGSPPVLTPGS LPPSQAAAKQDVKVFSEDGTSKVVE ILADMTARDLCQLLVYKSHCVDDNS WTLVEHHPHLGLERCLEDHELVVQV ESTMASESKFLFRKNYAKYEFFKNP MNFFPEQMVTWCQQSNGSQTQLLQN FLNSSSCPEIQGFLHVKELGKKSWK KLYVCLRRSGLYCSTKGTSKEPRHL QLLADLEDSNIFSLIAGRKQYNAPT DHGLCIKPNKVRNETKELRLLCAED EQTRTCWMTAFRLLKYGMLLYQNYR IPQQRKALLSPFSTPVRSVSENSLV AMDFSGQTGRVIENPAEAQSAALEE GHAWRKRSTRMNILGSQSPLHPSTL STVIHRTQHWFHGRISREESHRIIK QQGLVDGLFLLRDSQSNPKAFVLTL CHHQKIKNFQILPCEDDGQTFFSLD DGNTKFSDLIQLVDFYQLNKGVLPC KLKHHCIRVAL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
Official Symbol : GRB10
Synonyms : GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID : 2887
mRNA Refseq : NM_001001549
Protein Refseq : NP_001001549
MIM : 601523
UniProt ID : Q13322

Not For Human Consumption!

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