Recombinant Human GRB10 cell lysate

• Cat.No.: GRB10-751HCL

Specification

• Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
• Official Symbol: GRB10
• Synonyms: GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207
• Gene ID: 2887
• mRNA Refseq: NM_001001549
• Protein Refseq: NP_001001549
• MIM: 601523
• UniProt ID: Q13322
• Chromosome Location: 7p12.2
• Pathway: EGFR1 Signaling Pathway, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Kit Receptor Signaling Pathway, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem
• Function: SH3/SH2 adaptor activity; insulin receptor binding; protein binding