Recombinant Human GRB10 cell lysate

Cat.No. : GRB10-751HCL
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  • Gene Information
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Description : The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
Official Symbol : GRB10
Synonyms : GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID : 2887
mRNA Refseq : NM_001001549
Protein Refseq : NP_001001549
MIM : 601523
UniProt ID : Q13322
Chromosome Location : 7p12.2
Pathway : EGFR1 Signaling Pathway, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Kit Receptor Signaling Pathway, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem;
Function : SH3/SH2 adaptor activity; insulin receptor binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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