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Recombinant Human GRB10 cell lysate
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Cat.No. : | GRB10-751HCL Optional Service: Optional requirements on this protein |
Description : | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Species : | Human |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name : | GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ] |
Official Symbol : | GRB10 |
Synonyms : | GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207; |
Gene ID : | 2887 |
mRNA Refseq : | NM_001001549 |
Protein Refseq : | NP_001001549 |
MIM : | 601523 |
UniProt ID : | Q13322 |
Chromosome Location : | 7p12.2 |
Pathway : | EGFR1 Signaling Pathway, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; Kit Receptor Signaling Pathway, organism-specific biosystem; PDGFR-beta signaling pathway, organism-specific biosystem; |
Function : | SH3/SH2 adaptor activity; insulin receptor binding; protein binding; |
◆ Recombinant Protein
GRB10-246H | Recombinant Human GRB10 Protein, His-tagged | +Inquiry |
Grb10-1053M | Recombinant Mouse Grb10 Protein, MYC/DDK-tagged | +Inquiry |
GRB10-2233H | Recombinant Human GRB10 Protein, MYC/DDK-tagged | +Inquiry |
GRB10-5035H | Recombinant Human GRB10 Protein, GST-tagged | +Inquiry |
GRB10-7245M | Recombinant Mouse GRB10 Protein | +Inquiry |
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