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| Cat.No.: | GRB10-5035H |
| Product Overview: | Human GRB10 full-length ORF ( NP_001001550.1, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description: | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq |
| Source: | Wheat Germ |
| Species: | Human |
| Tag : | GST |
| Molecular Mass: | 87.2 kDa |
| AA Sequence: | MNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNSSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL |
| Applications: | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
| Notes: | Best use within three months from the date of receipt of this protein. |
| Storage: | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer: | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name: | GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ] |
| Official Symbol: | GRB10 |
| Synonyms: | GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207; |
| Gene ID: | 2887 |
| mRNA Refseq: | NM_001001549 |
| Protein Refseq: | NP_001001549 |
| MIM: | 601523 |
| UniProt ID: | Q13322 |
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