Recombinant Human GRB10 Protein, GST-tagged

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Recombinant Human GRB10 Protein, GST-tagged

GRB10 Related Products

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Cat.No. : GRB10-5035H
Product Overview : Human GRB10 full-length ORF ( NP_001001550.1, 1 a.a. - 536 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 87.2 kDa
AA Sequence : MNASLESLYS ACSMQSDTVP LLQNGQHARS QPRASGPPRS IQPQVSPRQR VQRSQPVHIL AVRRLQEEDQ QFRTSSLPAI PNPFPELCGP GSPPVLTPGS LPPSQAAAKQ DVKVFSEDGT SKVVEILADM TARDLCQLLV YKSHCVDDNS WTLVEHHPHL GLERCLEDHE LVVQVESTMA SESKFLFRKN YAKYEFFKNP MNFFPEQMVT WCQQSNGSQT QLLQNFLNSS SCPEIQGFLH VKELGKKSWK KLYVCLRRSG LYCSTKGTSK EPRHLQLLAD LEDSNIFSLI AGRKQYNAPT DHGLCIKPNK VRNETKELRL LCAEDEQTRT CWMTAFRLLK YGMLLYQNYR IPQQRKALLS PFSTPVRSVS ENSLVAMDFS GQTGRVIENP AEAQSAALEE GHAWRKRSTR MNILGSQSPL HPSTLSTVIH RTQHWFHGRI SREESHRIIK QQGLVDGLFL LRDSQSNPKA FVLTLCHHQK IKNFQILPCE DDGQTFFSLD DGNTKFSDLI QLVDFYQLNK GVLPCKLKHH CIRVAL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GRB10 growth factor receptor-bound protein 10 [ Homo sapiens ]
Official Symbol : GRB10
Synonyms : GRB10; growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR; RSS; IRBP; MEG1; GRB-IR; Grb-10; KIAA0207;
Gene ID : 2887
mRNA Refseq : NM_001001549
Protein Refseq : NP_001001549
MIM : 601523
UniProt ID : Q13322

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