Recombinant Full Length Human HGS Protein, C-Flag-tagged

• Cat.No.: HGS-1993HFL
• Product Overview: Recombinant Full Length Human HGS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 86 kDa
• AA Sequence: MGRGSGTFERLLDKATSQLLLETDW ESILQICDLIRQGDTQAKYAVNSIK KKVNDKNPHVALYALEVMES VVKNCGQTVHDEVANKQTMEELKDL LKRQVEVNVRNKILYLIQAWAHAFR NEPKYKVVQDTYQIMKVEGH VFPEFKESDAMFAAERAPDWVDAEE CHRCRVQFGVMTRKHHCRACGQIFC GKCSSKYSTIPKFGIEKEVR VCEPCYEQLNRKAEGKATSTTELPP EYLTSPLSQQSQLPPKRDETALQEE EELQLALALSQSEAEEKERL RQKSTYTSYPKAEPMPSASSAPPAS SLYSSPVNSSAPLAEDIDPELARYL NRNYWEKKQEEARKSPTPSA PVPLTEPAAQPGEGHAAPTNVVENP LPETDSQPIPPSGGPFSEPQFHNGE SEESHEQFLKALQNAVTTFV NRMKSNHMRGRSITNDSAVLSLFQS INGMHPQLLELLNQLDERRLYYEGL QDKLAQIRDARGALSALREE HREKLRRAAEEAERQRQIQLAQKLE IMRQKKQEYLEVQRQLAIQRLQEQE KERQMRLEQQKQTVQMRAQM PAFPLPYAQLQAMPAAGGVLYQPSG PASFPSTFSPAGSVEGSPMHGVYMS QPAPAAGPYPSMPSTAADPS MVSAYMYPAGATGAQAAPQAQAGPT ASPAYSSYQPTPTAGYQNVASQAPQ SLPAISQPPQSSTMGYMGSQ SVSMGYQPYNMQNLMTTLPSQDASL PPQQPYIAGQQPMYQQMAPSGGPPQ QQPPVAQQPQAQGPPAQGSE AQLISFD TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis

Gene Information

• Gene Name: HGS hepatocyte growth factor-regulated tyrosine kinase substrate [ Homo sapiens (human) ]
• Official Symbol: HGS
• Synonyms: HRS
• Gene ID: 9146
• mRNA Refseq: NM_004712.5
• Protein Refseq: NP_004703.1
• MIM: 604375
• UniProt ID: O14964