Recombinant Full Length Human KRT81 Protein, GST-tagged

Cat.No. : KRT81-5836HF
Product Overview : Human KRTHB1 full-length ORF ( AAH21241, 1 a.a. - 202 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 47.96 kDa
Protein Length : 202 amino acids
AA Sequence : MKATVIRHGETLRRTKEEINELNRM IQRLTAEVENAKCQNSKLEAAVAQS EQQGEAALSDARCKLAELEGALQKA KQDMACLIREYQEVMNSKLGLDIEI ATYRRLLEGEEQRLCEGIGAVNVCV SSSRGGVVCGDLCVSGSRPVTGSVC SAPCNGNVAVSTGLCAPCGQLNTTC GGGSCGVGSCGISSLGVGSCGSSCR KC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : KRT81 keratin 81 [ Homo sapiens ]
Official Symbol : KRT81
Synonyms : KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1; K81; ghHb1; MLN 137; keratin-81; hair keratin K2.9; type-II keratin Kb21; keratin, hair, basic, 1; hard keratin, type II, 1; type II hair keratin Hb1; metastatic lymph node 137 gene protein; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1;
Gene ID : 3887
mRNA Refseq : NM_002281
Protein Refseq : NP_002272
MIM : 602153
UniProt ID : Q14533

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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