Recombinant Full Length Human KRT81 Protein, GST-tagged

• Cat.No.: KRT81-5836HF
• Product Overview: Human KRTHB1 full-length ORF ( AAH21241, 1 a.a. - 202 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 47.96 kDa
• Protein length: 202 amino acids
• AA Sequence: MKATVIRHGETLRRTKEEINELNRM IQRLTAEVENAKCQNSKLEAAVAQS EQQGEAALSDARCKLAELEGALQKA KQDMACLIREYQEVMNSKLGLDIEI ATYRRLLEGEEQRLCEGIGAVNVCV SSSRGGVVCGDLCVSGSRPVTGSVC SAPCNGNVAVSTGLCAPCGQLNTTC GGGSCGVGSCGISSLGVGSCGSSCR KC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KRT81 keratin 81 [ Homo sapiens ]
• Official Symbol: KRT81
• Synonyms: KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1; K81; ghHb1; MLN 137; keratin-81; hair keratin K2.9; type-II keratin Kb21; keratin, hair, basic, 1; hard keratin, type II, 1; type II hair keratin Hb1; metastatic lymph node 137 gene protein; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1
• Gene ID: 3887
• mRNA Refseq: NM_002281
• Protein Refseq: NP_002272
• MIM: 602153
• UniProt ID: Q14533