Recombinant Human KRT81 Protein, GST-tagged KRT81-4796H

Recombinant Human KRT81 Protein, GST-tagged

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Recombinant Human KRT81 Protein, GST-tagged

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Cat.No. : KRT81-4796H
Product Overview : Human KRTHB1 full-length ORF ( AAH21241, 1 a.a. - 202 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.96 kDa
AA Sequence : MKATVIRHGETLRRT KEEINELNRMIQRLT AEVENAKCQNSKLEA AVAQSEQQGEAALSD ARCKLAELEGALQKA KQDMACLIREYQEVM NSKLGLDIEIATYRR LLEGEEQRLCEGIGA VNVCVSSSRGGVVCG DLCVSGSRPVTGSVC SAPCNGNVAVSTGLC APCGQLNTTCGGGSC GVGSCGISSLGVGSC GSSCRKC
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : KRT81 keratin 81 [ Homo sapiens ]
Official Symbol : KRT81
Synonyms : KRT81; keratin 81; keratin, hair, basic, 1 , KRTHB1; keratin, type II cuticular Hb1; hard keratin type II 1; Hb 1; K81; ghHb1; MLN 137; keratin-81; hair keratin K2.9; type-II keratin Kb21; keratin, hair, basic, 1; hard keratin, type II, 1; type II hair keratin Hb1; metastatic lymph node 137 gene protein; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1;
Gene ID : 3887
mRNA Refseq : NM_002281
Protein Refseq : NP_002272
MIM : 602153
UniProt ID : Q14533

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