Recombinant Full Length Human LGALS3 Protein, C-Flag-tagged

• Cat.No.: LGALS3-392HFL
• Product Overview: Recombinant Full Length Human LGALS3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 26 kDa
• AA Sequence: MADNFSLHDALSGSGNPNPQGWPGA WGNQPAGAGGYPGASYPGAYPGQAP PGAYPGQAPPGAYHGAPGAY PGAPAPGVYPGPPSGPGAYPSSGQP SAPGAYPATGPYGAPAGPLIVPYNL PLPGGVVPRMLITILGTVKP NANRIALDFQRGNDVAFHFNPRFNE NNRRVIVCNTKLDNNWGREERQSVF PFESGKPFKIQVLVEPDHFK
  VAVNDAHLLQYNHRVKKLNEISKLG ISGDIDLTSASYTMITRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein

Gene Information

• Gene Name: LGALS3 galectin 3 [ Homo sapiens (human) ]
• Official Symbol: LGALS3
• Synonyms: L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2
• Gene ID: 3958
• mRNA Refseq: NM_002306.4
• Protein Refseq: NP_002297.2
• MIM: 153619
• UniProt ID: P17931