Recombinant Full Length Human MEF2C Protein, C-Flag-tagged

• Cat.No.: MEF2C-671HFL
• Product Overview: Recombinant Full Length Human MEF2C Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 51 kDa
• AA Sequence: MGRKKIQITRIMDERNRQVTFTKRK FGLMKKAYELSVLCDCEIALIIFNS TNKLFQYASTDMDKVLLKYT EYNEPHESRTNSDIVETLRKKGLNG CDSPDPDADDSVGHSPESEDKYRKI NEDIDLMISRQRLCAVPPPN FEMPVSIPVSSHNSLVYSNPVSSLG NPNLLPLAHPSLQRNSMSPGVTHRP PSAGNTGGLMGGDLTSGAGT SAGNGYGNPRNSPGLLVSPGNLNKN MQAKSPPPMNLGMNNRKPDLRVLIP PGSKNTMPSVSEDVDLLLNQ RINNSQSAQSLATPVVSVATPTLPG QGMGGYPSAISTTYGTEYSLSSADL SSLSGFNTASALHLGSVTGW QQQHLHNMPPSALSQLGACTSTHLS QSSNLSLPSTQSLNIKSEPVSPPRD RTTTPSRYPQHTRHEAGRSP
  VDSLSSCSSSYDGSDREDHRNEFHS PIGLTRPSPDERESPSVKRMRLSEG WATTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors
• Protein Pathways: MAPK signaling pathway

Gene Information

• Gene Name: MEF2C myocyte enhancer factor 2C [ Homo sapiens (human) ]
• Official Symbol: MEF2C
• Synonyms: NEDHSIL; DEL5q14.3; C5DELq14.3
• Gene ID: 4208
• mRNA Refseq: NM_002397.5
• Protein Refseq: NP_002388.2
• MIM: 600662
• UniProt ID: Q06413