| Description : |
This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
Flag |
| Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : |
51.5 kDa |
| AA Sequence : |
MMAAAPIQQNGTHTGVPIDLDPPDS RKRPLEAPPEAGSTKRTNTGEDGQY FLKVLIPSYAAGSIIGKGGQ TIVQLQKETGATIKLSKSKDFYPGT TERVCLIQGTVEALNAVHGFIAEKI REMPQNVAKTEPVSILQPQT TVNPDRIKQTLPSSPTTTKSSPSDP MTTSRANQVKIIVPNSTAGLIIGKG GATVKAVMEQSGAWVQLSQK PDGINLQERVVTVSGEPEQNRKAVE LIIQKIQEDPQSGSCLNISYANVTG PVANSNPTGSPYANTAEVLP TAAAAAGLLGHANLAGVAAFPAVLS GFTGNDLVAITSALNTLASYGYNLN TLGLGLSQAAATGALAAAAA SANPAAAAANLLATYASEASASGST AGGTAGTFALGSLAAATAATNGYFG AASPLAASAILGTEKSTDGS KDVVEIAVPENLVGAILGKGGKTLV EYQELTGARIQISKKGEFVPGTRNR KVTITGTPAATQAAQYLITQ
RITYEQGVRAANPQKVGTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade. |
| Concentration : |
>50 ug/mL as determined by microplate BCA method. |
| Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
