Recombinant Full Length Human NR4A2 Protein, C-Flag-tagged

• Cat.No.: NR4A2-371HFL
• Product Overview: Recombinant Full Length Human NR4A2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 66.4 kDa
• AA Sequence: MPCVQAQYGSSPQGASPASQSYSYH SSGEYSSDFLTPEFVKFSMDLTNTE ITATTSLPSFSTFMDNYSTG YDVKPPCLYQMPLSGQQSSIKVEDI QMHNYQQHSHLPPQSEEMMPHSGSV YYKPSSPPTPTTPGFQVQHS PMWDDPGSLHNFHQNYVATTHMIEQ RKTPVSRLSLFSFKQSPPGTPVSSC QMRFDGPLHVPMNPEPAGSH HVVDGQTFAVPNPIRKPASMGFPGL QIGHASQLLDTQVPSPPSRGSPSNE GLCAVCGDNAACQHYGVRTC EGCKGFFKRTVQKNAKYVCLANKNC PVDKRRRNRCQYCRFQKCLAVGMVK EVVRTDSLKGRRGRLPSKPK SPQEPSPPSPPVSLISALVRAHVDS NPAMTSLDYSRFQANPDYQMSGDDT QHIQQFYDLLTGSMEIIRGW AEKIPGFADLPKADQDLLFESAFLE LFVLRLAYRSNPVEGKLIFCNGVVL HRLQCVRGFGEWIDSIVEFS SNLQNMNIDISAFSCIAALAMVTER HGLKEPKRVEELQNKIVNCLKDHVT FNNGGLNRPNYLSKLLGKLP ELRTLCTQGLQRIFYLKLEDLVPPP AIIDKLFLDTLPFSGPTRTRPLEQK LISEEDLAANDILDYKDDDD
  KVSGPTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Gene Information

• Gene Name: NR4A2 nuclear receptor subfamily 4 group A member 2 [ Homo sapiens (human) ]
• Official Symbol: NR4A2
• Synonyms: NOT; RNR1; HZF-3; IDLDP; NURR1; TINUR
• Gene ID: 4929
• mRNA Refseq: NM_006186.4
• Protein Refseq: NP_006177.1
• MIM: 601828
• UniProt ID: P43354