Recombinant Full Length Human NRAS Protein, GST tagged
Cat.No. : | NRAS-6750HF |
Product Overview : | Recombinant Full Length Human NRAS Protein with GST tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Molecular Mass : | The protein has a calculated MW of 53 kDa. |
AA Sequence : | MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDGSTSG SGHHHHHHSAGLVPRGSTAIGMKET AAAKFERQHMDSPDLGTGGGSGDDD DKSPMTEYKLVVVGAGGVGKSALTI QLIQNHFVDEYDPTIEDSYRKQVVI DGETCLLDILDTAGQEEYSAMRDQY MRTGEGFLCVFAINNSKSFADINLY REQIKRVKDSDDVPMVLVGNKCDLP TRTVDTKQAHELAKSYGIPFIETSA KTRQGVEDAFYTLVREIRQYRMKKL NSSDDGTQGCMGLPCVVM |
Endotoxin : | < 1 EU/μg by LAL |
Purity : | > 85% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Sterile 50 mM Tris, 200 mM NaCl, 0.5M GSH, pH 8.0 |
Gene Name : | NRAS neuroblastoma RAS viral (v-ras) oncogene homolog [ Homo sapiens (human) ] |
Official Symbol : | NRAS |
Synonyms : | NRAS; neuroblastoma RAS viral (v-ras) oncogene homolog; GTPase NRas; N ras; N-ras protein part 4; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog; NS6; ALPS4; N-ras; NRAS1 |
Gene ID : | 4893 |
mRNA Refseq : | NM_002524 |
Protein Refseq : | NP_002515 |
MIM : | 164790 |
UniProt ID : | P01111 |
Products Types
◆ Recombinant Protein | ||
NRAS-30411TH | Recombinant Human NRAS Protein | +Inquiry |
NRAS-01H | Active Recombinant Human NRAS Protein, His-tagged | +Inquiry |
NRAS-0940H | Recombinant Human NRAS Protein (M1-K169), Biotinylated tagged | +Inquiry |
NRAS-1544H | Recombinant Human NRAS Protein, His (Fc)-Avi-tagged | +Inquiry |
NRAS-0932H | Recombinant Human NRAS Protein (T2-K169, Q61K), Tag Free | +Inquiry |
◆ Lysates | ||
NRAS-3702HCL | Recombinant Human NRAS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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