Recombinant Full Length Human PPP2CA Protein, C-Flag-tagged

• Cat.No.: PPP2CA-577HFL
• Product Overview: Recombinant Full Length Human PPP2CA Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 35.4 kDa
• AA Sequence: MDEKVFTKELDQWIEQLNECKQLSE SQVKSLCEKAKEILTKESNVQEVRC PVTVCGDVHGQFHDLMELFR IGGKSPDTNYLFMGDYVDRGYYSVE TVTLLVALKVRYRERITILRGNHES RQITQVYGFYDECLRKYGNA NVWKYFTDLFDYLPLTALVDGQIFC LHGGLSPSIDTLDHIRALDRLQEVP HEGPMCDLLWSDPDDRGGWG ISPRGAGYTFGQDISETFNHANGLT LVSRAHQLVMEGYNWCHDRNVVTIF SAPNYCYRCGNQAAIMELDD
  TLKYSFLQFDPAPRRGEPHVTRRTP DYFLTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Phosphatase, Transcription Factors
• Protein Pathways: Long-term depression, Oocyte meiosis, TGF-beta signaling pathway, Tight junction, Wnt signaling pathway

Gene Information

• Gene Name: PPP2CA protein phosphatase 2 catalytic subunit alpha [ Homo sapiens (human) ]
• Official Symbol: PPP2CA
• Synonyms: RP-C; PP2Ac; PP2CA; NEDLBA; PP2Calpha
• Gene ID: 5515
• mRNA Refseq: NM_002715.4
• Protein Refseq: NP_002706.1
• MIM: 176915
• UniProt ID: P67775