Recombinant Full Length Human SARM1 Protein, C-Flag-tagged
Cat.No. : | SARM1-41HFL |
Product Overview : | Recombinant Full Length Human SARM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 79.2 kDa |
AA Sequence : | MVLTLLLSAYKLCRFFAMSGPRPGA ERLAVPGPDGGGGTGPWWAAGGRGP REVSPGAGTEVQDALERALP ELQQALSALKQAGGARAVGAGLAEV FQLVEEAWLLPAVGREVAQGLCDAI RLDGGLDLLLRLLQAPELET RVQAARLLEQILVAENRDRVARIGL GVILNLAKEREPVELARSVAGILEH MFKHSEETCQRLVAAGGLDA VLYWCRRTDPALLRHCALALGNCAL HGGQAVQRRMVEKRAAEWLFPLAFS KEDELLRLHACLAVAVLATN KEVEREVERSGTLALVEPLVASLDP GRFARCLVDASDTSQGRGPDDLQRL VPLLDSNRLEAQCIGAFYLC AEAAIKSLQGKTKVFSDIGAIQSLK RLVSYSTNGTKSALAKRALRLLGEE VPRPILPSVPSWKEAEVQTW LQQIGFSKYCESFREQQVDGDLLLR LTEEELQTDLGMKSGITRKRFFREL TELKTFANYSTCDRSNLADW LGSLDPRFRQYTYGLVSCGLDRSLL HRVSEQQLLEDCGIHLGVHRARILT AAREMLHSPLPCTGGKPSGD TPDVFISYRRNSGSQLASLLKVHLQ LHGFSVFIDVEKLEAGKFEDKLIQS VMGARNFVLVLSPGALDKCM QDHDCKDWVHKEIVTALSCGKNIVP IIDGFEWPEPQVLPEDMQAVLTFNG IKWSHEYQEATIEKIIRFLQ GRSSRDSSAGSDTSLEGAAPMGPTS GPTRTRRLEQKLISEEDLAANDILD YKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | SARM1 sterile alpha and TIR motif containing 1 [ Homo sapiens (human) ] |
Official Symbol : | SARM1 |
Synonyms : | SARM; HsTIR; SAMD2; hSARM1; MyD88-5 |
Gene ID : | 23098 |
mRNA Refseq : | NM_015077.4 |
Protein Refseq : | NP_055892.2 |
MIM : | 607732 |
UniProt ID : | Q6SZW1 |
Products Types
◆ Recombinant Protein | ||
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Sarm1-5690M | Recombinant Mouse Sarm1 Protein, Myc/DDK-tagged | +Inquiry |
SARM1-3893R | Recombinant Rhesus Macaque SARM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SARM1-273H | Recombinant Human SARM1 Protein, MYC/DDK-tagged | +Inquiry |
SARM1-1954H | Recombinant Human SARM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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