Recombinant Full Length Human TGFBI Protein, C-Flag-tagged

• Cat.No.: TGFBI-924HFL
• Product Overview: Recombinant Full Length Human TGFBI Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 72.4 kDa
• AA Sequence: MALFVRLLALALALALGPAATLAGP AKSPYQLVLQHSRLRGRQHGPNVCA VQKVIGTNRKYFTNCKQWYQ RKICGKSTVISYECCPGYEKVPGEK GCPAALPLSNLYETLGVVGSTTTQL YTDRTEKLRPEMEGPGSFTI FAPSNEAWASLPAEVLDSLVSNVNI ELLNALRYHMVGRRVLTDELKHGMT LTSMYQNSNIQIHHYPNGIV TVNCARLLKADHHATNGVVHLIDKV ISTITNNIQQIIEIEDTFETLRAAV AASGLNTMLEGNGQYTLLAP TNEAFEKIPSETLNRILGDPEALRD LLNNHILKSAMCAEAIVAGLSVETL EGTTLEVGCSGDMLTINGKA IISNKDILATNGVIHYIDELLIPDS AKTLFELAAESDVSTAIDLFRQAGL GNHLSGSERLTLLAPLNSVF KDGTPPIDAHTRNLLRNHIIKDQLA SKYLYHGQTLETLGGKKLRVFVYRN SLCIENSCIAAHDKRGRYGT LFTMDRVLTPPMGTVMDVLKGDNRF SMLVAAIQSAGLTETLNREGVYTVF APTNEAFRALPPRERSRLLG DAKELANILKYHIGDEILVSGGIGA LVRLKSLQGDKLEVSLKNNVVSVNK EPVAEPDIMATNGVVHVITN
  VLQPPANRPQERGDELADSALEIFK QASAFSRASQRSVRLAPVYQKLLER MKHTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane

Gene Information

• Gene Name: TGFBI transforming growth factor beta induced [ Homo sapiens (human) ]
• Official Symbol: TGFBI
• Synonyms: CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
• Gene ID: 7045
• mRNA Refseq: NM_000358.3
• Protein Refseq: NP_000349.1
• MIM: 601692
• UniProt ID: Q15582