Recombinant Full Length Human UGT2B15 Protein, C-Flag-tagged

• Cat.No.: UGT2B15-996HFL
• Product Overview: Recombinant Full Length Human UGT2B15 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a glycosyltransferase that is invovled in the metabolism and elimination of toxic compounts, both endogenous and of xenobiotic origin. This gene plays a role in the regulation of estrogens and androgens. This locus is present in a cluster of similar genes and pseudogenes on chromosome 4.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 60.9 kDa
• AA Sequence: MSLKWTSVFLLIQLSCYFSSGSCGK VLVWPTEYSHWINMKTILEELVQRG HEVTVLTSSASTLVNASKSS AIKLEVYPTSLTKNYLEDSLLKILD RWIYGVSKNTFWSYFSQLQELCWEY YDYSNKLCKDAVLNKKLMMK LQESKFDVILADALNPCGELLAELF NIPFLYSLRFSVGYTFEKNGGGFLF PPSYVPVVMSELSDQMIFME RIKNMIHMLYFDFWFQIYDLKKWDQ FYSEVLGRPTTLFETMGKAEMWLIR TYWDFEFPRPFLPNVDFVGG LHCKPAKPLPKEMEEFVQSSGENGI VVFSLGSMISNMSEESANMIASALA QIPQKVLWRFDGKKPNTLGS NTRLYKWLPQNDLLGHPKTKAFITH GGTNGIYEAIYHGIPMVGIPLFADQ HDNIAHMKAKGAALSVDIRT MSSRDLLNALKSVINDPVYKENVMK LSRIHHDQPMKPLDRAVFWIEFVMR HKGAKHLRVAAHNLTWIQYH
  SLDVIAFLLACVATVIFIITKFCLF CFRKLAKKGKKKKRDTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Androgen and estrogen metabolism, Ascorbate and aldarate metabolism, Drug metabolism - cytochrome P450, Drug metabolism - other enzymes, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Pentose and glucuronate interconversions, Porphyrin and chlorophyll metabolism, Retinol metabolism, Starch and sucrose metabolism

Gene Information

• Gene Name: UGT2B15 UDP glucuronosyltransferase family 2 member B15 [ Homo sapiens (human) ]
• Official Symbol: UGT2B15
• Synonyms: HLUG4; UGT2B8; UDPGTH3; UDPGT 2B8; UDPGT2B15
• Gene ID: 7366
• mRNA Refseq: NM_001076.4
• Protein Refseq: NP_001067.2
• MIM: 600069
• UniProt ID: P54855