Recombinant Full Length Rabbit T-Lymphocyte Activation Antigen Cd86(Cd86) Protein, His-Tagged

• Cat.No.: RFL77OF
• Product Overview: Recombinant Full Length Rabbit T-lymphocyte activation antigen CD86(CD86) Protein (P42071) (23-330aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Oryctolagus cuniculus (Rabbit)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (23-330)
• AA Sequence: AASLRIQAYFNKTADLPCQFTNSQS RSLSELVVFWQDQERLVLYELFLGR EKPDNVDPKYIGRTSFDQESWNLQL HNVQIKDKGVYQCFVHHRGAKGLVP IYQMNSELSVLANFTQPEITLISNI TRNSAINLTCSSVQGYPEPKKMFFV LKTENATTEYDGVIEKSQDNVTGLY NISISGSITFSDDIRNATIYCVLQT ESTETYSQHFPIVPADPVPVEKPRL WIAAVALTLIVVCGIVLFLTLWKRK KEQQPGVCECETIKMDKAENEHVEE RVKIHEPEKIPAKAAKCEHRLKTPS SDKSAAHF
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: CD86
• Synonyms: CD86; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD antigen CD86
• UniProt ID: P42071

Gene Information

• Gene Name: CD86
• Synonyms: CD86; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD antigen CD86
• UniProt ID: P42071

Reviews

01/09/2022

With the CD86 protein's high-quality composition and reliability, researchers can confidently proceed with their studies, knowing that they have access to a protein that consistently delivers accurate results.

05/30/2021

Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.

12/08/2017

The CD86 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.

Q&As

Are there any ongoing clinical trials involving CD86 inhibitors?

Yes, several clinical trials are investigating the efficacy of CD86 inhibitors in various diseases, including autoimmune disorders and certain cancers.

How does CD86 contribute to transplant medicine?

In transplantation, CD86 blockade is investigated as a potential strategy to modulate the immune response and prevent graft rejection by inhibiting excessive T cell activation.

How does CD86 influence the balance between Th1 and Th2 immune responses?

CD86 signaling is involved in the differentiation of T helper cells. Modulating CD86 levels may influence the balance between Th1 and Th2 responses, which is relevant in various immune-mediated diseases.

Can CD86 be used as a prognostic marker in certain diseases?

There is emerging evidence suggesting that CD86 expression levels may have prognostic value in certain diseases, guiding clinicians in predicting disease outcomes.

How does CD86 influence the development of regulatory T cells (Tregs)?

CD86 signaling is involved in the development and function of regulatory T cells, which play a crucial role in maintaining immune tolerance and preventing autoimmune reactions.