Recombinant Full Length Rat T-Cell-Specific Surface Glycoprotein Cd28(Cd28) Protein, His-Tagged

• Cat.No.: RFL17688RF
• Product Overview: Recombinant Full Length Rat T-cell-specific surface glycoprotein CD28(Cd28) Protein (P31042) (20-218aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Rattus norvegicus (Rat)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (20-218)
• AA Sequence: NKILVKQSPLLVVDNNEVSLSCRYS YNLLAKEFRASLYKGVNSDVEVCVG NGNFTYQPQFRPNVGFNCDGNFDNE TVTFRLWNLDVNHTDIYFCKIEVMY PPPYLDNEKSNGTIIHIKEKHLCHA QTSPKLFWPLVVVAGVLLCYGLLVT VTLCIIWTNSRRNRLLQSDYMNMTP RRLGPTRKHYQPYAPARDFAAYRP
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: Cd28
• Synonyms: Cd28; T-cell-specific surface glycoprotein CD28; CD antigen CD28
• UniProt ID: P31042

Gene Information

• Gene Name: Cd28
• Synonyms: Cd28; T-cell-specific surface glycoprotein CD28; CD antigen CD28
• UniProt ID: P31042

Reviews

08/24/2021

Its unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.

08/24/2021

Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.

08/06/2021

the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.

Q&As

Can CD28 protein be used for personalized medicine?

CD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.

What are the potential clinical applications of targeting CD28 protein?

Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.

How does CD28 protein impact regulatory T cells (Tregs)?

CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.

How does CD28 protein impact cancer immunotherapy?

CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.

Are there any approved therapies targeting CD28 protein?

Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.