| Description : |
Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
65.2 kDa |
| AA Sequence : |
MESNHKSGDGLSGTQKEAALRALVQ RTGYSLVQENGQRKYGGPPPGWDAA PPERGCEIFIGKLPRDLFEDELIPL CEKIGKIYEMRMMMDFNGNNRGYAF VTFSNKVEAKNAIKQLNNYEIRNGR LLGVCASVDNCRLFVGGIPKTKKRE EILSEMKKVTEGVVDVIVYPSAADK TKNRGFAFVEYESHRAAAMARRKLL PGRIQLWGHGIAVDWAEPEVEVDED TMSSVKILYVRNLMLSTSEEMIEKE FNNIKPGAVERVKKIRDYAFVHFSN REDAVEAMKALNGKVLDGSPIEVTL AKPVDKDSYVRYTRGTGGRGTMLQG EYTYSLGQVYDPTTTYLGAPVFYAP QTYAAIPSLHFPATKGHLSNRAIIR APSVREIYMNVPVGAAGVRGLGGRG YLAYTGLGRGYQVKGDKREDKLYDI LPGMELTPMNPVTLKPQGIKLAPQI LEEICQKNNWGQPVYQLHSAIGQDQ RQLFLYKITIPALASQNPAIHPFTP PKLSAFVDEAKTYAAEYTLQTLGIP TDGGDGTMATAAAAATAFPGYAVPN ATAPVSAAQLKQAVTLGQDLAAYTT YEVYPTFAVTARGDGYGTFTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
