Recombinant Human ABCC8 Protein, MYC/DDK-tagged
Cat.No. : | ABCC8-238H |
Product Overview : | Recombinant human ABCC8 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 176.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ATP binding cassette subfamily C member 8 [ Homo sapiens ] |
Official Symbol : | ABCC8 |
Synonyms : | ABC36; HHF1; HI; HRINS; MRP8; PHHI; SUR; SUR1; SUR1delta2; TNDM2 |
Gene ID : | 6833 |
mRNA Refseq : | NM_000352.3 |
Protein Refseq : | NP_000343.2 |
MIM : | 600509 |
UniProt ID : | Q09428 |
Products Types
◆ Recombinant Protein | ||
ABCC8-243H | Recombinant Human ABCC8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABCC8-592H | Recombinant Human ABCC8 Protein, Myc/DDK-tagged | +Inquiry |
Abcc8-1460M | Recombinant Mouse Abcc8 Protein, Myc/DDK-tagged | +Inquiry |
ABCC8-63R | Recombinant Rat ABCC8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ABCC8-301376H | Recombinant Human ABCC8 protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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