Recombinant Human ABCG4 Protein, GST-Tagged

• Cat.No.: ABCG4-068H
• Product Overview: Human ABCG4 full-length ORF ( AAH41091, 1 a.a. - 646 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein is a member of the White subfamily and plays an important role in cellular cholesterol homeostasis. This protein functions as either a homodimer or as a heterodimer with another ABC subfamily protein such as ABCG1. [provided by RefSeq, Jan 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 96.8 kDa
• AA Sequence: MAEKALEAVGCGLGPGAVAMAVTLE DGAEPPVLTTHLKKVENHITEAQRF SHLPKRSAVDIEFVELSYSVREGPC WRKRGYKTLLKCLSGKFCRRELIGI MGPSGAGKSTFMNILAGYRESGMKG QILVNGRPRELRTFRKMSCYIMQDD MLLPHLTVLEAMMVSANLKLSEKQE VKKELVTEILTALGLMSCSHTRTAL LSGGQRKRLAIALELVNNPPVMFFD EPTSGLDSASCFQVVSLMKSLAQGG RTIICTIHQPSAKLFEMFDKLYILS QGQCIFKGVVTNLIPYLKGLGLHCP TYHNPADFIIEVASGEYGDLNPMLF RAVQNGLCAMAEKKSSPEKNEVPAP CPPCPPEVDPIESHTFATSTLTQFC ILFKRTFLSILRDTVLTHLRFMSHV VIGVLIGLLYLHIGDDASKVFNNTG CLFFSMLFLMFAALMPTVLTFPLEM AVFMREHLNYWYSLKAYYLAKTMAD VPFQVVCPVVYCSIVYWMTGQPAET SRFLLFSALATATALVAQSLGLLIG AASNSLQVATFVGPVTAIPVLLFSG FFVSFKTIPTYLQWSSYLSYVRYGF EGVILTIYGVERGDLTCLEERCPFR EPQSILRALDVEDAKLYMDFLVLGI FFLALRLLAYLVLRYRVKSER
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 [ Homo sapiens ]
• Official Symbol: ABCG4
• Synonyms: WHITE2
• Gene ID: 64137
• mRNA Refseq: NM_022169
• Protein Refseq: NP_071452
• MIM: 607784
• UniProt ID: Q9H172