Recombinant Human Activin A Receptor, Type I

Cat.No. : ACVR1-2743H
Product Overview : Recombinant HumanACVR1 protein is expressed inNicotiana benthamiana.
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Cat. No. : ACVR1-2743H
Description : Activins are homodimers or heterodimers of the various b subunit isoforms, belonging to the TGFb family. Mature Activin a has two 116 amino acids residues βA subunits (βA - βA). Activin exhibits a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins plays a key role in the production and regulation of hormones such as FSH, LH, GnRH and ACTH.
Source : Nicotiana benthamiana.
MW : recombinant protein βA chain, monomeric form 14.54 kDa containing 116 amino acid residues.
Endotoxin Level : < 0.04 EU/ μg protein (LAL method).
Formulation : Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
Storage : This lyophilized preparation is stable at 2-80C, but should be kept at –200C for long termstorage. Repeated freezing and thawing is not recommended.
Gene Name : ACVR1 activin A receptor, type I [ Homo sapiens ]
Synonyms :
ACVR1; activin A receptor, type I; OTTHUMP00000204604; OTTHUMP00000204626; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 2; activin receptor type I; activin receptor type-1; activin receptor-like kinase 2; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor R1; EC 2.7.11.30
Gene ID : 90
mRNA Refseq : NM_001105
Protein Refseq : NP_001096
MIM : 102576
UniProt ID : Q04771
Chromosome Location : 2q23-q24
Pathway : Cytokine-cytokine receptor interaction; TGF-beta signaling pathway
Function : ATP binding; contributes_to activin receptor activity, type I; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta binding; protein homodimerization activity

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