Recombinant Human Activin A Receptor, Type I

Cat.No. : ACVR1-2743H
Product Overview : Recombinant HumanACVR1 protein is expressed inNicotiana benthamiana.
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Cat. No. : ACVR1-2743H
Description : Activins are homodimers or heterodimers of the various b subunit isoforms, belonging to the TGFb family. Mature Activin a has two 116 amino acids residues βA subunits (βA - βA). Activin exhibits a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins plays a key role in the production and regulation of hormones such as FSH, LH, GnRH and ACTH.
Source : Nicotiana benthamiana.
MW : recombinant protein βA chain, monomeric form 14.54 kDa containing 116 amino acid residues.
Endotoxin Level : < 0.04 EU/ μg protein (LAL method).
Formulation : Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
Storage : This lyophilized preparation is stable at 2-80C, but should be kept at –200C for long termstorage. Repeated freezing and thawing is not recommended.
Gene Name : ACVR1 activin A receptor, type I [ Homo sapiens ]
Synonyms :
ACVR1; activin A receptor, type I; OTTHUMP00000204604; OTTHUMP00000204626; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 2; activin receptor type I; activin receptor type-1; activin receptor-like kinase 2; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor R1; EC
Gene ID : 90
mRNA Refseq : NM_001105
Protein Refseq : NP_001096
MIM : 102576
UniProt ID : Q04771
Chromosome Location : 2q23-q24
Pathway : Cytokine-cytokine receptor interaction; TGF-beta signaling pathway
Function : ATP binding; contributes_to activin receptor activity, type I; transmembrane receptor protein serine/threonine kinase activity; transforming growth factor beta binding; protein homodimerization activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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