Recombinant Human acyl-CoA binding domain containing 6, His-tagged
|Product Overview :
|ACBD6, 1-282 aa, Human, His tag, E.coli
- Gene Information
- Related Products
|ACBD6 contains 1 ACB (acyl-CoA-binding) domain and 2 ANK repeats. This protein binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1 CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. It does not bind fatty acids. Recombinant human ASCC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
|Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
|Molecular Mass :
|33.5 kDa (305aa) confirmed by MALDI-TOF
|AA Sequence :
|MGSSHHHHHH SSGLVPRGSH MGSMASSFLP AGAITGDSGG ELSSGDDSGE VEFPHSPEIE ETSCLAELFE KAAAHLQGLI QVASREQLLY LYARYKQVKV GNCNTPKPSF FDFEGKQKWE AWKALGDSSP SQAMQEYIAV VKKLDPGWNP QIPEKKGKEA NTGFGGPVIS SLYHEETIRE EDKNIFDYCR ENNIDHITKA IKSKNVDVNV KDEEGRALLH WACDRGHKEL VTVLLQHRAD INCQDNEGQT ALHYASACEF LDIVELLLQS GADPTLRDQD GCLPEEVTGC KTVSLVLQRH TTGKA
|>90% by SDS - PAGE
|Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
|0.5mg/ml (determined by Bradford assay)
|Gene Name :
|ACBD6 acyl-CoA binding domain containing 6 [ Homo sapiens ]
|Official Symbol :
|ACBD6; acyl-CoA binding domain containing 6; acyl Coenzyme A binding domain containing 6; acyl-CoA-binding domain-containing protein 6; MGC2404; acyl-Coenzyme A binding domain containing 6;
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|Chromosome Location :
|binding; fatty-acyl-CoA binding;
|◆ Recombinant Protein
|Recombinant Mouse ACBD6 Protein, His (Fc)-Avi-tagged
|Recombinant Rhesus Macaque ACBD6 Protein, His (Fc)-Avi-tagged
|Recombinant Rat ACBD6 Protein, His (Fc)-Avi-tagged
|Recombinant Mouse ACBD6 Protein
|Recombinant Rat ACBD6 Protein
|Recombinant Human ACBD6 cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Genetic mutations of the ACBD6 gene preventing the production of a full-length protein are associated with neurodegenerative syndromes in humans.
HeLa ACBD6.KO cells that do not produce the ACBD6 protein are viable, but the acylation of lipids is significantly reduced which leads to a defect in formation of lipid droplets. The deficiency of the myristoylation reaction in the absence of an NMT/ACBD6 complex is evidenced by a decrease of the in vivo rate of protein myristoylation, and by the increased sensitivity of the cells to NMT inhibitors.
Yes, our recombinant ACBD6 protein may be suitable for crystallization studies or other structural biology applications, but this will depend on the specific protein fragment, preparation, and experimental conditions.
It may have potential application in developing diagnostic assays. However, our recombinant proteins are for research use only and not for clinical use.
The recommended amount of recombinant ACBD6 protein to use in experiments varies depending on the specific application and experiment design.
The recommended level of endotoxin for the Recombinant ACBD6 Protein varies depending on the specific application and experimental requirements. Typically, however, it is recommended to use a protein with endotoxin levels of less than 0.1 EU/μg. Creative BioMart supports recombinant protein production with different endotoxin levels.
ACBD6 expression has been detected in a wide range of cell types, including liver, kidney, heart, and brain tissues. However, the level of expression may vary depending on the cell type and physiological conditions.
Yes, the recombinant ACBD6 protein can be used to generate antibodies, which can be used for a variety of applications, including Western blotting, ELISA, and immunohistochemistry. However, it is important to optimize the experimental conditions for antibody generation, such as the choice of adjuvants and the immunization protocol, to obtain high-quality antibodies with the desired specificity and sensitivity.
It is suitable for a variety of applications, including biochemical assays, enzyme kinetics studies, protein-protein interaction studies, and structural biology studies.
Yes, there are several alternative or related proteins that can be used as a control when using the recombinant ACBD6 protein in experiments. For example, a control protein with similar biochemical properties.
Customer Reviews (3)Write a review
The quality of the recombinant human ACBD6 protein from Creative BioMart is exceptional. I highly recommend it to anyone conducting research in this field.
I purchased the recombinant ACBD6 protein from Creative BioMart and it was reasonably priced compared to other suppliers. The fast delivery and great customer service were a bonus.
The technical support team at Creative BioMart was very helpful in assisting me with my order of the Recombinant ACBD6 Protein. Their expertise was invaluable.
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