Recombinant Human ADAMTS12 Protein, GST-tagged

• Cat.No.: ADAMTS12-298H
• Product Overview: Human ADAMTS12 full-length ORF ( AAH58841.1, 1 a.a. - 229 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 52.4 kDa
• AA Sequence: MPCAQRSWLANLSVVAQLLNFGALC YGRQPQPGPVRFPDRRQEHFIKGLP EYHVVGPVRVDASGHFLSYGLHYPI TSSRRKRDLDGSEDWVYYRISHEEK DLFFNLTVNQGFLSNSYIMEKRYGN LSHVKMMASSAPLCHLSGTVLQQGT RVGTAALSACHGLTGFFQLPHGDFF IEPVKKHPLVEGGYHPHIVYRRQKV PETKEPTCGLKGIVTHMSSWVEESV LFFW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 [ Homo sapiens ]
• Official Symbol: ADAMTS12
• Synonyms: ADAMTS12; ADAM metallopeptidase with thrombospondin type 1 motif, 12; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12; A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS12; ADAMTS-12; ADAM-TS 12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12; PRO4389
• Gene ID: 81792
• mRNA Refseq: NM_030955
• Protein Refseq: NP_112217
• MIM: 606184
• UniProt ID: P58397