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Recombinant Human AGR2 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | AGR2-3191H |
| Product Overview : | AGR2 MS Standard C13 and N15-labeled recombinant protein (NP_006399) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 19.8 kDa |
| AA Sequence : | MEKIPVSAFL LLVALSYTLA RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELTRTRP LEQKLISEED LAANDILDYK DDDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | AGR2 anterior gradient 2, protein disulphide isomerase family member [ Homo sapiens (human) ] |
| Official Symbol : | AGR2 |
| Synonyms : | AGR2; anterior gradient 2 homolog (Xenopus laevis); anterior gradient protein 2 homolog; AG2; HAG 2; PDIA17; protein disulfide isomerase family A; member 17; XAG 2; AG-2; HPC8; anterior gradient homolog 2; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog; protein disulfide isomerase family A, member 17; GOB-4; HAG-2; XAG-2; |
| Gene ID : | 10551 |
| mRNA Refseq : | NM_006408 |
| Protein Refseq : | NP_006399 |
| MIM : | 606358 |
| UniProt ID : | O95994 |
◆ Recombinant Protein
| AGR2-520H | Recombinant Human AGR2 Protein, MYC/DDK-tagged | +Inquiry |
| Agr2-1560M | Recombinant Mouse Agr2 Protein, Myc/DDK-tagged | +Inquiry |
| Agr2-502R | Recombinant Rat Agr2 Protein, His-tagged | +Inquiry |
| AGR2-9481H | Recombinant Human AGR2, GST-tagged | +Inquiry |
| AGR2-2046Z | Recombinant Zebrafish AGR2 | +Inquiry |
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◆ Lysates
| AGR2-8972HCL | Recombinant Human AGR2 293 Cell Lysate | +Inquiry |
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