Recombinant Human AIMP2 Protein (1-320 aa), His-tagged

• Cat.No.: AIMP2-2030H
• Product Overview: Recombinant Human AIMP2 Protein (1-320 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.

Specification

• Description: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 39.3 kDa
• Protein length: 1-320 aa
• AA Sequence: MPMYQVKPYHGGGAPLRVELPTCMY RLPNVHGRSYGPAPGAGHVQEESNL SLQALESRQDDILKRLYELKAAVDG LSKMIQTPDADLDVTNIIQADEPTT LTTNALDLNSVLGKDYGALKDIVIN ANPASPPLSLLVLHRLLCEHFRVLS TVHTHSSVKSVPENLLKCFGEQNKK QPRQDYQLGFTLIWKNVPKTQMKFS IQTMCPIEGEGNIARFLFSLFGQKH NAVNATLIDSWVDIAIFQLKEGSSK EKAAVFRSMNSALGKSPWLAGNELT VADVVLWSVLQQIGGCSVTVPANVQ RWMRSCENLAPFNTALKLLK
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [ Homo sapiens ]
• Official Symbol: AIMP2
• Synonyms: AIMP2; JTV 1; JTV1; p38; PRO0992; protein JTV-1; P38; JTV-1
• Gene ID: 7965
• mRNA Refseq: NM_006303
• Protein Refseq: NP_006294
• MIM: 600859
• UniProt ID: Q13155