Recombinant Human Albumin Protein, Low Endotoxin, Media Grade
Cat.No. : | ALB-02H |
Product Overview : | Recombinant Human Albumin Protein was expressed in Pichia pastoris. |
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Source : | Pichia pastoris |
Species : | Human |
Tag : | Non |
Form : | The protein was lyophilized from a concentrated (1mg/ml) solution with no additives. |
Molecular Mass : | 66.5±6.7 kDa |
AA Sequence : | CAS: 70024-90-7 |
Endotoxin : | ≤ 0.5 EU/mg |
Purity : | ≥ 99.0% (USP-NF2023) |
Host Cell Protein Residue : | ≤ 10 ng/g (ELISA) |
Notes : | pH: 6.4 - 7.4 |
Storage : | Store at 2-8°C, avoid light moisture-proof sealed dry, valid for 24 months. |
Reconstitution : | It is recommended to dissolve ARTrHA dry powder with aseptic PBS solution to 200 mg/ml, and then further dilute and subpack with other solvents. The sterile solution can be stored at 4 °C for 6-12 months. After opening, please use as soon as possible to avoid contamination. |
Gene Name : | ALB albumin [ Homo sapiens (human) ] |
Official Symbol : | ALB |
Synonyms : | ALB; albumin; HSA; PRO0883; PRO0903; PRO1341; serum albumin; EC 6.1.1.16 |
Gene ID : | 213 |
mRNA Refseq : | NM_000477 |
Protein Refseq : | NP_000468 |
MIM : | 103600 |
UniProt ID : | P02768 |
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Not For Human Consumption!
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Q&As (17)
Ask a questionYes, ALB protein levels can be used as a marker to monitor the response to treatment or progression of certain diseases. For instance, in liver diseases, ALB protein levels can be monitored to assess the effectiveness of treatment or progression of liver damage. Similarly, in diseases like nephrotic syndrome, monitoring ALB protein levels can help evaluate the response to therapy and disease progression. However, it is crucial to interpret ALB protein levels in conjunction with other clinical parameters and in consultation with a healthcare provider.
Yes, ALB protein has clinical significance beyond its basic functions. It has been associated with various health conditions and can serve as a prognostic marker. For example, low ALB protein levels have been linked to increased mortality risk in hospitalized patients and have been used as a prognostic marker for chronic diseases like heart failure and cancer. High ALB protein levels have also been associated with better outcomes in certain health conditions, such as in patients with traumatic brain injury.
Yes, several factors other than medical conditions can affect ALB protein levels. Age is one such factor, as ALB protein levels tend to decrease slightly with advancing age. Gender can also play a role, with studies suggesting that males may have slightly higher ALB protein levels compared to females. Additionally, certain lifestyle factors like smoking and excessive alcohol consumption have been associated with lower ALB protein levels. It is important to consider these factors when interpreting ALB protein levels in an individual.
The treatment of low ALB protein levels depends on the underlying cause. In cases of liver disease, treating the liver condition can help improve ALB protein levels. This may include lifestyle modifications, medication, or, in severe cases, liver transplantation. In instances of malnutrition or inadequate dietary intake, improving nutrition and incorporating protein-rich foods can help increase ALB protein levels.
ALB protein levels can be used as part of a comprehensive assessment for liver disease but are not usually used as a stand-alone screening tool. Liver function tests, which may include measuring ALB protein levels, as well as other markers like liver enzymes and bilirubin levels, can help evaluate liver health. However, a proper diagnosis of liver disease typically requires a combination of clinical evaluation, medical history, imaging studies, and additional laboratory tests.
Monitoring ALB protein levels is important in various diseases and conditions, particularly those involving liver or kidney dysfunction, malnutrition, inflammatory disorders, and conditions associated with protein loss or inflammation.
Yes, several medical conditions can affect ALB protein levels. Liver diseases, including cirrhosis, hepatitis, and liver failure, can lead to decreased ALB protein production. Kidney diseases, such as nephrotic syndrome or chronic kidney disease, can cause ALB protein loss through the urine. Inflammatory conditions like rheumatoid arthritis or systemic lupus erythematosus can also affect ALB protein levels. Additionally, malnutrition and certain cancers can contribute to low ALB protein levels.
The level of ALB protein in the body can be measured through a blood test called serum albumin test. This test measures the concentration of ALB protein in the blood and is commonly used to assess liver function and nutritional status.
Eating a balanced diet that includes an adequate amount of protein can help maintain ALB protein levels. Good sources of protein include lean meats, poultry, fish, eggs, dairy products, legumes, and nuts. However, it is always advisable to consult with a healthcare professional or registered dietitian for personalized dietary recommendations based on individual needs and underlying health conditions.
ALB protein levels generally remain relatively stable throughout the day. However, it is worth noting that certain factors, such as hydration status, can influence ALB levels. For example, dehydration can lead to a temporary increase in ALB concentration, while overhydration can lead to a temporary decrease. It is essential to consider the overall clinical context and interpret ALB protein levels in conjunction with other relevant clinical information.
Low ALB protein levels, also known as hypoalbuminemia, can indicate several underlying health conditions. It is commonly associated with liver diseases, such as cirrhosis, hepatitis, and liver failure. Other causes of low ALB protein levels include malnutrition, kidney disease, severe burns, inflammatory bowel disease, and certain types of cancer.
While low ALB protein levels are more commonly associated with health concerns, high ALB protein levels can also be a cause for concern in certain situations. Elevated ALB protein levels can occur in conditions such as dehydration, severe burns, and certain types of cancer. Additionally, high ALB protein levels can sometimes be an indicator of an underlying inflammatory process. It is important to consider the individual's overall clinical context and consult with a healthcare professional for proper evaluation and interpretation of elevated ALB protein levels.
Yes, ALB protein levels can decrease slightly during pregnancy. This is considered a normal physiological change, and the decrease in ALB protein levels is believed to be due to increased blood volume and fluid retention. However, significant or persistent decreases in ALB protein levels during pregnancy may require further evaluation.
Yes, genetic factors can influence ALB protein levels. Variations in genes involved in ALB protein synthesis or metabolism can contribute to differences in ALB protein levels among individuals. These genetic factors can be inherited and may affect an individual's baseline ALB protein levels. However, genetic factors alone may not account for significant changes in ALB protein levels, and additional factors like medical conditions, medications, and environmental factors should also be considered.
Yes, ALB protein levels are often used as an indicator of nutritional status. Since ALB protein is primarily synthesized by the liver and its production can be affected by nutrient deficiencies or malnutrition, low levels can suggest poor nutritional status. However, it is important to note that ALB protein levels can be influenced by various factors, and additional measurements and assessments may be needed to comprehensively evaluate nutritional status.
Yes, certain medications can affect ALB protein levels. Some medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and some antiepileptic medications, have been reported to potentially decrease ALB protein levels. However, it is essential to consult with a healthcare professional or pharmacist to understand the potential effects of specific medications on ALB protein levels.
High ALB protein levels, known as hyperalbuminemia, are less common than low levels and are usually not a cause for concern on their own. In some instances, high ALB protein levels can be seen in dehydration or certain medical conditions like severe burns or chronic inflammation. It is important to assess the underlying cause if hyperalbuminemia is observed in order to address any potential health issues.
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